Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models

Table 7 Physiological Parameters of Hfe ^+/ ⁺ and Hfe ^-/ ^- mice^a

	*Hfe* ^+/+			*Hfe* ^-/-
	N	Mean	(SD)	N	Mean	(SD)
Body weight (g)	4	23.4	(1.4)	4	22.9	(2.1)
Liver non-heme iron (μg/g tissue)	4	234.4	(26.1)	4	861.5*	(42.0)
Blood iron (μg/g tissue)	4	429.5	(7.0)	4	477.9*	(19.8)
Blood manganese (ng/g tissue)	4	15.8	(0.8)	4	11.5*	(0.8)

^a Four-month old female mice
* Significantly different between the two genotypes as determined by unpaired Student's t-test (p < 0.05)

ISSN: 1476-069X