Table 4 Subsample analysis: associations between ‘heart disease and stroke’ and noise adjusted for exposure to nitrogen dioxide

UK and Netherlands combined

Participants = 1411; Cases = 84

Crude (adjusted for country)

1.30 (0.98, 1.73)

1.22 (0.97, 1.53)

1.32 (0.92, 1.88)

Adjusted^a

1.17 (0.86, 1.59)

1.14 (0.89, 1.45)

1.28 (0.88, 1.87)

Adjusted^a plus nitrogen dioxide exposure

1.24 (0.90, 1.71)

1.22 (0.95, 1.58)

0.93 (0.57, 1.53)

% change in coefficient (absolute value)

37%

54%

127%

Sweden

Participants = 990; Cases = 53

Crude

0.71 (0.54, 0.94)

1.01 (0.71, 1.43)

1.21 (0.74, 1.99)

Adjusted^a

0.73 (0.54, 0.99)

0.88 (0.61, 1.27)

1.08 (0.64, 1.80)

Adjusted^a plus nitrogen dioxide exposure

0.74 (0.55, 1.01)

0.93 (0.62, 1.40)

0.99 (0.56, 1.73)

% change in coefficient (absolute value)

5%

46%

117%

≥ 20 years residence

UK and Netherlands combined

Participants = 828; Cases = 52

Crude (adjusted for country)

1.30 (0.91, 1.87)

1.38 (1.02, 1.86)

1.51 (0.97, 2.36)

Adjusted^a

1.19 (0.80, 1.77)

1.33 (0.96, 1.84)

1.49 (0.91, 2.43)

Adjusted^a plus nitrogen dioxide exposure

1.25 (0.82, 1.90)

1.43 (1.01, 2.01)

1.14 (0.61, 2.15)

% change in coefficient (absolute value)

29%

24%

67%

Sweden

Participants = 480; Cases = 35

Crude

0.93 (0.62, 1.38)

1.37 (0.87, 2.14)

0.95 (0.49, 1.86)

Adjusted^a

1.02 (0.64, 1.63)

1.29 (0.77, 2.15)

0.80 (0.39, 1.62)

Adjusted^a plus nitrogen dioxide exposure

1.03 (0.64, 1.65)

1.36 (0.78, 2.37)

0.72 (0.32, 1.62)

% change in coefficient (absolute value)

26%

21%

39%