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Table 4 Patterns of susceptibility to ETS in association with diabetes mellitus, in never smokers

From: Environmental tobacco smoke exposure and diabetes in adult never-smokers

Variable

Categories

ETS (yes vs. no) in never-smokers.OR (95% CI)

Age

≤ 50 years

0.32 (0.07, 1.60)

> 50 years

1.69 (1.10, 2.60)

Interaction

0.05

Sex

Males

1.23 (0.65, 2.35)

Females

1.71 (1.01, 2.92)

Interaction p-value

0.443

BMI (kg/m2)

< 25

1.15 (0.42, 3.19)

25-29

1.24 (0.68, 2.27)

≥30

1.97 (1.12, 3.46)

Interaction p-value

0.261

Hypertension

No

1.23 (0.56, 2.73)

Yes

1.64 (1.01, 2.66)

Interaction p-value

0.545

COPD (FEV1/FVC <0.7)

No

1.18 (0.75, 1.87)

Yes

4.55 (1.69, 12.3)

Interaction p-value

0.015

Educational level

≤ 9 years

1.38 (0.44, 4.31)

>9 years

1.52 (0.98, 2.36)

Interaction

0.254

Vigorous physical activity

<0.5 hours/week

1.88 (1.09, 3.19)

≥0.5 hours/week

1.05 (0.62, 1.79)

Interaction p-value

0.160

Triglyceride level (mmol/l)

≤ 1.52

0.89 (0.38, 2.10)

> 1.52

1.85 (1.13, 3.02)

Interaction p-value

0.149

HDL level (mmol/l)

≤ 1.51

1.59 (0.96, 2.61)

> 1.51

1.34 (0.61, 2.94)

Interaction p-value

0.718

C-reactive protein (mg/l)

≤1.0

1.71 (0.83, 3.56)

>1.0

1.47 (0.89, 2.45)

Interaction p-value

0.742

Menopause

No

0.56 (0.07, 4.33)

Yes

2.14 (1.13, 4.05)

Interaction p-value

0.217

  1. OR: odds ratio, CI: confidence interval; COPD: chronic obstructive pulmonary disease, FEV1: forced expiratory volume in 1 second, FVC: forced vital capacity. HDL: high density lipoproteins. OR values represent % increase in prevalent diabetes for ETS exposure in never smokers in each category. Triglyceride and C-reactive protein were grouped by its median value while HDL was grouped by its mean value. Area was treated as a random effect in all models. Group-specific estimates were obtained from a single model. P-values of interaction terms (between exposure and potential effect modifiers) were obtained from a separate model.