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Table 5 Comparative basal gene expressions in various tissues. a

From: Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians

  

Tissues

Function

Gene

Hippocampus

Liver

Kidney

Muscles

Mitochondrial metabolism

CoxI

65.103 ± 11.103

2048 ± 1354

8192 ± 1214

104.104 ± 84.104

Oxidative stress

Sod2

8 ± 6.8

256 ± 104

128 ± 8.5

2048 ± 279

 

Sod3

4 ± 1.9

2 ± 1.4

16 ± 2.2

8 ± 4.3

Detoxication process

Mt1

8 ± 2.5

4 ± 1.3

4 ± 0.9

4 ± 3.8

 

Mt2

1024 ± 430

64 ± 3

64 ± 33

512 ± 482

 

Gsta4

32 ± 27

512 ± 4.9

32 ± 4.4

256 ± 51

Apoptosis

Bax

8 ± 3.2

16 ± 2.1

16 ± 8.8

512 ± 189

 

Fos

4 ± 3.7

0.25 ± 0.01

0.5 ± 0.4

16 ± 9.5

  1. a Gene expressions in brain, liver, kidneys, and skeletal muscles from control mice after one month feeding with vegetal diet (mean ± SE, n = 3). B-actin was the reference gene.
  2. Bax: Bcl2-associated X protein; Cox I: cytochrome c oxidase subunit I; fos: FBJ osteosarcoma oncogene; Gsta4: glutathione S-transferase, alpha 4; Mt1: metallothionein isoform 1; Mt2: metallothionein isoform 2; Sod2: mitochondrial superoxide dismutase; Sod3: extracellular superoxide dismutase.
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Environmental Health

ISSN: 1476-069X