Skip to main content

Table 5 Odds ratio of breast cancer risk associated with serum levels of OCPs

From: Serum levels of environmental pollutants is a risk factor for breast cancer in Inuit: a case control study

 

Unadjusted

Adjusted

 

Continuous

(μg/kg lipid)

Continuous

(μg/kg lipid)

1st Tertile

2nd Tertile

3rd Tertile

∑OCP (OR (95% CI))

1.00

1.00 (1.00; 1.00)

1.00 (reference)

1.05 (0.47; 2.39)

1.90 (0.88; 4.07)

 n (cases/controls)

75/84

75/84

19/28

20/28

36/28

p-value

0.002

0.002

 

0.902

0.101

Cis-Nonachlor (OR (95% CI))

1.01

1.01 (1.00; 1.01)

1.00 (reference)

1.31 (0.58; 2.96)

2.07 (0.96; 4.47)

 n (cases/controls)

76/84

76/84

18/29

22/27

36/28

p-value

0.008

0.008

 

0.512

0.063

Trans-Nonachlor (OR (95% CI))

1.00

1.00 (1.00; 1.00)

1.00 (reference)

1.00 (0.44; 2.25)

1.80 (0.84; 3.84)

 n (cases/controls)

76/84

76/84

20/28

20/28

36/28

p-value

0.002

0.002

 

1.000

0.128

HCB (OR (95% CI))

1.00

1.00 (1.00; 1.00)

1.00 (reference)

0.86 (0.38; 1.94)

1.76 (0.83; 3.73)

 n (cases/controls)

76/84

76/84

21/28

23/28

32/28

p-value

0.062

0.062

 

0.712

0.138

Mirex (OR (95% CI))

1.01

1.01 (1.00; 1.02)

1.00 (reference)

1.42 (0.65; 3.12)

1.58 (0.73; 3.44)

 n (cases/controls)

76/84

76/84

19/28

27/28

30/28

p-value

0.026

0.026

 

0.381

0.250

Oxychlordane (OR (95% CI))

1.00

1.00 (1.00; 1.00)

1.00 (reference)

1.11 (0.49; 2.49)

1.90 (0.88; 4.07)

 n (cases/controls)

76/84

76/84

19/28

21/28

36/28

p-value

0.005

0.005

 

0.809

0.101

p,p’DDE (OR (95% CI))

1.00

1.00 (1.00; 1.00)

1.00 (reference)

1.69 (0.75; 3.80)

2.06 (0.93; 4.56)

 n (cases/controls)

76/84

76/84

16/28

27/28

33/28

p-value

0.002

0.002

 

0.206

0.074

p,p’DDT (OR (95% CI))

1.01

1.01 (1.00; 1.03)

1.00 (reference)

1.52 (0.67; 3.42)

2.07 (0.95; 4.52)

 n (cases/controls)

75/84

75/84

17/29

24/27

34/28

p-value

0.074

0.074

 

0.315

0.067

βHCH(OR (95% CI))

1.01

1.01 (1.00; 1.03)

1.00 (reference)

1.11 (0.49; 2.49)

1.90 (0.88; 4.07)

 n (cases/controls)

76/84

76/84

19/28

21/28

36/28

p-value

0.071

0.071

 

0.809

0.101

  1. n: number of observations per group; OR: odds ratio; 95% CI: 95% confidence interval; Unadjusted analysis: Only OR, and not 95% CI, were reported for unadjusted data; Adjusted: adjusted for confounders identified by change in estimate, following confounders were considered age, BMI, cotinine levels, parity, and breastfeeding; Bold text: significant finding, OR significantly different from 1; ∑OCP: p,p′-DDT, p,p′-DDE, mirex, β-HCH, HCB, cis- and trans-nonachlor, and oxychlordane