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Table 1 Key entities a notifier relies on when determining a substance’s use is GRAS.

From: Out of balance: conflicts of interest persist in food chemicals determined to be generally recognized as safe

 

2015

(n = 51)1

2016

(n = 65)

2017

(n = 70)

2018

(n = 73)

2019

(n = 67)

2020

(n = 77)

Average

(total = 403)

GRAS panel organized by notifier or third-party

60%

70%

61%

45%

49%

62%

57%

Employee of notifier

26%

19%

33%

32%

38%

32%

30%

Employee of third-party

14%

11%

6%

23%

14%

6%

13%

  1. 1 Number of GRAS notices filed by FDA in the given year