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Table 1 Characteristics of elderly white men from the Normative Aging Study, 2000–2013

From: Long-term exposure to ambient fine particulate components and leukocyte epigenome-wide DNA Methylation in older men: the Normative Aging Study

Variables

First visit (N = 669)

Second visit (N = 387)

Third visit (N = 121)

Fourth visit (N = 1)

All visits (N = 1,178)

Age, Mean ± SD

74 ± 7

76 ± 7

80 ± 6

76 ± NA

75 ± 7

BMI (kg/m2), Mean ± SD

28.10 ± 4.07

27.94 ± 4.33

27.84 ± 4.26

24.68 ± NA

28.02 ± 4.18

Years of education, Mean ± SD

15.07 ± 3.01

15.29 ± 3.08

15.84 ± 3.07

13.00 ± NA

15.22 ± 3.05

Smoking status, n (%)

 Never

205 (30.64%)

118 (30.49%)

37 (30.58%)

0 (0%)

360 (30.56%)

 Ever

464 (69.36%)

269 (69.51%)

84 (69.42%)

1 (100%)

818 (69.44%)

 Pack-years, Mean ± SD

25.43 ± 21.38

20.48 ± 23.86

20.01 ± 23.52

15.00 ± NA

20.94 ± 24.71

Alcohol consumption (drinks/day), n (%)

 ˂ 2

540 (80.72%)

318 (82.17%)

100 (82.64%)

0 (0%)

958 (81.32%)

  ≥ 2

129 (19.28%)

69 (17.83%)

21 (17.36%)

1 (100%)

220 (18.68%)

Estimated cell type (%), Mean ± SD

 Granulocytes

57.51 ± 9.24

58.83 ± 10.07

61.91 ± 8.66

63.35 ± NA

58.40 ± 9.55

 Monocytes

10.75 ± 2.74

10.16 ± 3.08

10.31 ± 2.60

9.49 ± NA

10.51 ± 2.85

 B cells

1.63 ± 2.75

1.20 ± 2.37

1.11 ± 2.44

0.62 ± NA

1.43 ± 2.60

 CD4 + T lymphocytes

8.42 ± 4.39

8.31 ± 4.76

7.37 ± 3.40

15.53 ± NA

8.28 ± 4.43

 CD8 + T lymphocytes

8.70 ± 3.15

8.52 ± 3.17

7.40 ± 2.83

6.95 ± NA

8.51 ± 3.14

 Natural killer cells

7.11 ± 3.86

7.57 ± 4.35

7.42 ± 4.11

4.19 ± NA

7.29 ± 4.05

  1. Abbreviations: BMI body mass index, SD standard deviation