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Table 3 The number of significantly differentially methylated probes, regions, and pathways from annual exposure to 14 PM2.5 components and 4 sources

From: Long-term exposure to ambient fine particulate components and leukocyte epigenome-wide DNA Methylation in older men: the Normative Aging Study

Exposures

DMPs

DMRs

Pathways

PM2.5 components

 Br

58

34

2

 Ca

1

5

16

 Cu

13

10

3

 EC

0

6

8

 Fe

6

6

2

 K

11

18

9

 Ni

8

22

4

 NO3−

15

3

46

 OC

2

2

6

 Pb

0

3

2

 Si

10

1

7

 SO42−

7

3

3

 V

5

11

27

 Zn

7

10

8

Sources

 Source 1 (biomass burning)

10

0

8

 Source 2 (all traffic)

8

5

0

 Source 3 (secondary particles)

19

5

2

 Source 4 (coal burning and heavy fuel oil combustion)

14

7

7

  1. Abbreviations: PM2.5 fine particulate matter with an aerodynamic diameter ≤ 2.5 µm, Br bromine, Ca calcium, Cu copper, EC element carbon, Fe iron, K potassium, Ni nickel, NO3− nitrate, OC organic carbon, Pb lead, Si silicon, SO42− sulfate, V vanadium, Zn zinc