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Table 4 Neuropsychological measures by Gulf War illness status

From: Cognitive decrements in 1991 Gulf War veterans: associations with Gulf War illness and neurotoxicant exposures in the Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) cohorts

   

GWI Cases

(n = 312)

  

Controls

(n = 99)

  

p-value

  

Unadjusted Mean (SD)

Adjusted Mean (SE)

95% CI

Unadjusted Mean (SD)

Adjusted Mean (SE)

95% CI

β

Attention/processing speed

CPT 3 Omissions

49.76(10.07)

48.56(0.76)

47.07, 50.05

47.27(9.36)

46.73(1.15)

44.46, 48.99

1.83

0.1349

CPT 3 Commissions*

53.38(10.52)

50.37(0.77)

48.85, 51.88

47.78(9.93)

47.45(1.17)

45.15, 49.75

2.92

0.0193

CPT 3 Hit Reaction Time Raw Score

421.44(81.76)

425.09(6.32)

412.66, 437.52

431.81(74.97)

425.56(9.60)

406.68, 444.45

-0.48

0.9628

D-KEFS trial 1 time (sec)*

32.6(7.82)

31.15(0.55)

30.08, 32.22

29.67(6.55)

28.98(0.85)

27.32, 30.65

2.17

0.0151

D-KEFS trial 1 self-corrected errors*

0.36(0.71)

0.34(0.05)

0.25, 0.44

0.17(0.41)

0.18(0.08)

0.04, 0.33

0.16

0.0427

D-KEFS trial 1 uncorrected errors

0.16(0.58)

0.10(0.04)

0.02, 0.18

0.07(0.46)

0.01(0.06)

-0.12, 0.14

0.09

0.1944

D-KEFS trial 2 time (sec)*

24.17(5.65)

23.21(0.39)

22.43, 23.98

21.57(4.40)

21.19(0.61)

20.00, 22.39

2.01

0.0017

D-KEFS trial 2 self-corrected errors

0.17(0.45)

0.19(0.03)

0.12, 0.25

0.17(0.43)

0.19(0.05)

0.09, 0.29

-0.01

0.9266

D-KEFS trial 2 uncorrected errors

0.05(0.26)

0.04(0.19)

-0.33, 0.41

0.52(5.03)

0.30(0.29)

-0.27, 0.88

-0.26

0.3890

TMT Trail A: Time (sec)

32.00(13.58)

25.30(0.98)

23.36, 27.25

27.46(10.02)

25.21(1.30)

22.63, 27.79

0.09

0.9494

Verbal Memory

CVLT-II Correct in Trials 1–5*

46.43(10.28)

47.97(0.73)

46.53, 49.41

50.52(9.79)

51.77(1.13)

49.54, 54.00

-3.8

0.0015

CVLT-II Correct in short delay free recall*

9.39(3.28)

9.88(0.23)

9.42, 10.33

10.56(3.04)

10.89(0.36)

10.18, 11.60

-1.0

0.0077

CVLT-II Correct in long delay free recall*

9.72(3.41)

10.22(0.25)

9.73, 10.70

10.93(3.17)

11.27(0.38)

10.51, 12.02

-1.1

0.0095

Executive Functioning

D-KEFS trial 3 time (sec)*

62.01(16.23)

60.11(1.14)

57.88, 62.35

57.71(14.88)

56.34(1.76)

52.88, 59.81

3.77

0.0420

D-KEFS trial 3 self-corrected errors

0.82(1.39)

0.75(0.10)

0.56, 0.94

0.59(1.00)

0.58(0.15)

0.28, 0.87

0.18

0.2696

D-KEFS trail 3 uncorrected errors

0.75(3.14)

0.65(0.21)

0.24, 1.07

0.37(1.13)

0.28(0.33)

-0.37, 0.93

0.37

0.2817

D-KEFS trial 4 time (sec)*

67.53(19.31)

65.02(1.35)

62.37, 67.67

60.68(15.80)

60.24(2.09)

56.13, 64.35

4.78

0.0300

D-KEFS trial 4 self-corrected errors

0.85(1.13)

0.89(0.08)

0.73, 1.04

0.63(0.85)

0.72(0.12)

0.47, 0.96

0.17

0.1995

D-KEFS trial 4 uncorrected errors

1.06(1.77)

0.87(0.22)

0.44, 1.31

1.14(5.05)

1.07(0.34)

0.39, 1.74

-0.20

0.5868

TMT Trail B: Time (sec)

73.50(29.44)

63.88(3.32)

57.32, 70.44

64.74(31.64)

57.55(4.40)

48.84, 66.25

6.33

0.2007

  1. Multiple Logistic Regression modeling was used for analysis in the table adjusting for age, gender, years of education, race/ethnicity and study site. Beta is the regression parameter representing the difference in adjusted means. p-value testing whether beta = 0, or equivalently a difference in adjusted means. Abbreviations: SD (standard deviation), SE (standard error of the mean), CI (confidence interval). CIs are shown for adjusted means
  2. *p < 0.05
  3. **p < 0.001