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Table 3 Results from mixed linear models & logistic regression of 1-year PM2.5, O3, NO2 and kidney function among a random sample of NC CARES serum creatinine laboratory results (N = 44,486)

From: Associations between long-term exposure to air pollution and kidney function utilizing electronic healthcare records: a cross-sectional study

 

IQR 1-year PM2.5 (µg/m3)

IQR 1-year O3 (ppb)

IQR 1-year NO2 (ppb)

eGFRcr (mL/min/1.73m2) β (95% CI)

 Model 1

-1.44 (-1.72, -1.15)

-0.32 (-0.56, -0.08)

0.80 (0.34, 1.25)

 Model 2

-1.63 (-1.96, -1.31)

0.28 (0.00 0.55)

0.48 (0.03, 0.92)

CKD aOR (95% CI)

 Model 1

0.87 (0.73, 1.05)

0.91 (0.84, 1.00)

0.73 (0.66, 0.80)

 Model 2

1.04 (0.88, 1.22)

0.89 (0.78, 1.01)

0.79 (0.68, 0.92)

  1. aModel 1 Estimate with only random intercepts for patients and spline adjustment for temporal variation
  2. bModel 2 fully adjusted linear mixed model estimate for temporal variations, age, sex, race, comorbidities, and census block group
  3. cIQR for exposures in our eGFRcr analysis are: PM2.5 – 1.43 µg/m3; O3 – 2.81 ppb; NO2 – 8.49 ppb
  4. dIQR for exposures in our CKD analysis are: PM2.5 – 3.39 µg/m3; O3 – 3.36 ppb; NO2 – 10.45 ppb
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Environmental Health

ISSN: 1476-069X