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Table 3 Association between urinary porphyrine concentrsations and the study variables (age, sex, alcohol, smoking, years of residence, and organochlorintaed compounds in serum).

From: Serum organochlorines and urinary porphyrin pattern in a population highly exposed to hexachlorobenzene

 

TP

Copro I

Copro III

Uro I + UroIII

 

Median (25%–75%)

Detectables n (%)

Median (25%-75%) †

Detectables n (%)

Median (25%-75%) †

Detectables n (%)

Age

      

   <45

117 (73–185)

70 (79)

7 (3–15)

85 (96)

29 (11–46)

31 (35)

   45–64

89 (62–132)

62 (74)

4 (0.5–8)

67 (80)

14 (4.5–27.5)

24 (29)

   >64

83 (56–126)*

51 (75)

4 (1.3–9)*

56 (82)*

12.5 (3–30)*

27 (40)

Sex

      

   Female

85 (62–112)

42 (69)

5 (0.5–11)

60 (98)

20 (10–31)

17 (28)

   Male

107 (65–165)*

141 (78)

5 (2–11)

148 (82)*

19 (5–37)

65 (36)

Alcohol

      

   No

99 (62–144)

52 (71)

5 (0.5–11)

67 (92)

18 (6–35)

23 (32)

   Ocasional

86 (64–143)

45 (74)

5 (0.5–10)

52 (85)

19 (7–35)

21 (34)

   Habitual

103 (66–162)

86 (80)

5 (3–12)

89 (83)

20 (5–35)

38 (36)

Smoking

      

   Never

86 (62–124)

52 (71)

5 (0.5–10)

64 (88)

19 (6–29)

19 (26)

   Ocasional + Ex

92 (60–146)

65 (70)

4 (0.5–10)

76 (82)

12 (4–35)

33 (35)

   < 20 cigs./day

103 (83–159)

30 (91)

6 (4–9)

28 (85)

20 (7–39)

12 (36)

   ≥ 20 cigs./day

127 (81–588)*

36 (86)*

6.5 (3.5–15)

40 (95)

32 (12–46)*

18 (43)

Years living in Flix

      

   ≤ 20 years

165 (86, 240)

21 (91)

7 (3, 19)

22 (95)

27 (17,51)

10 (43)

   > 20 years

94 (62, 143)*

162 (74)

5 (0.5, 10)*

186 (85)

19 (6, 34)*

72 (33)

HCB ng/ml (tertiles)

      

   <16.1

129 (81–176)

60 (77)

7 (2–15)

73 (94)

26 (8–43)

29 (37)

   16.1–29.5

82 (55–126)

62 (75)

4 (0.5–10)

70 (84)

18 (5–31)

28 (34)

   >29.5

92 (64–130)*

61 (76)

5 (2–8.5)*

65 (81)*

14 (5–31.5)*

25 (31)

DDE ng/ml (tertiles)

      

   < 3.22

124 (74–179)

62 (78)

7 (2–15)

74 (94)

26 (7–49)

31 (39)

   3.22 – 9.88

105 (65–161)

60 (75)

4 (0.5–10)

64 (80)

20 (4.5–35)

22 (28)

   > 9.88

82 (57–117)*

61 (74)

5 (2–8.5)*

70 (85)

12 (5–26)*

29 (35)

PCBs ng/ml (tertiles)

      

   < 2.08

108 (74, 166)

63 (80)

6 (2–13)

72 (91)

22 (7, 35)

21 (27)

   2.08–4.89

99 (61, 172)

60 (77)

4 (2–12)

69 (88)

20 (6, 38)

30 (38)

   > 4.89

87 (59, 130)*

60 (73)

4.5 (0.5–9)

67 (80)*

13.5 (4, 30)*

31 (37)

CB-138 (tertiles)

      

   < 0.55

108 (73–116)

63 (79)

5.5 (2.5–13)

73 (91)

20 (7.5–36.5)

19 (24)

   0.55 – 1.29

99 (61–146)

63 (80)

5 (2–12)

69 (87)

21 (6–38)

36 (46)

   > 1.29

89 (60–130)*

57 (70)

4 (0.5–9)

66 (80)*

13 (4–29)*

27 (33)

CB-153 (tertiles)

      

   < 0.61

109 (73–161)

65 (81)

6 (3–13.5)

74 (93)

21 (8.5–35)

21 (26)

   0.61 – 1.36

98 (61–173)

58 (73)

4 (0.5–11)

66 (84)

20 (5–39)

30 (38)

   > 1.36

87 (61–130)

60 (73)

4 (0.5–9)*

68 (83)

13 (5–32)

31 (38)

CB-180 (tertiles)

      

   < 0.61

110 (73–168)

64 (80)

5 (2–11.5)

72 (90)

21 (7–38.5)

22 (28)

   0.61 – 1.80

94 (61–143)

59 (75)

5 (0.5–12)

73 (92)

20 (6–37)

26 (33)

   > 1.80

90 (60–141)*

60 (73)

4.5 (0.5–10)

63 (77)*

14 (3–29)*

34 (41)

  1. TP: total porphyrins; CPI, CPIII: coproporphyrins I, III; UPI, UPIII: uroporphyrins I, III. * p < 0.05 using the extension of the non-parametric Wilcoxon test for linear trend † non-detectable values were set at the median value between 0 and the detectable level