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Table 5 Studies on urinary porphyrins in human populations exposed to moderate levels of hexachlorobenzene (HCB).

From: Serum organochlorines and urinary porphyrin pattern in a population highly exposed to hexachlorobenzene

    

Porphyrins

 

Author year/country (ref)

N

Period

Serum-HCB (range in ng/mL)

UP

CP

Comments

WORKERS

      

   Morley 1973/Australia [6]

54

1950's-60's

NA

NS

NS

only 1 worker with high UP

   Burns 1974/USA [7]

20

1973–74

<1–310

NS

NS

-

   Currier 1980/USA [8]

50

1974–7

3–1121

NS

↓ CP if HCB > 200

   Selden 1999/Sweden [21]

27

1980's

NA(9E/18NE)

NS

↑ CPIII in E vs NE

GENERAL POPULATION

      

NEONATES

      

   Ozalla 2002/Spain [18]

68

1997–99

0.4–21

NS

↓ CPI and CPIII

ADULTS

      

   Burns 1975/USA [20]

120

1972

0–23

NS

-

   This study/Spain

242

1994

2–1616

NS

↓ CPI and CPIII

  1. NA: not available. NS: no statistically significant difference. UP: uroporphyrins. CP, CPI and CPIII: coproporphyrins total, I and III. E/NE: number of subjects exposed/non-exposed