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Table 3 Univariate analysis for factors associated with genotoxicity assays performed with urine extracts on HepG2 cells: statistical significance of associations (N = 64).

From: Integrated exposure assessment of sewage workers to genotoxicants: an urinary biomarker approach and oxidative stress evaluation

Independent variables P-value
  Tail DNA percent MNi/1000 BNed
Socio-demographic characteristics   
   Marital status (married/not married) 0.12 0.94
   Smoking (ex-smokers/never smokers) 0.16 0.18
Educational level; years (> 12/≤ 12) 0.04 0.23
Age; years (≤ 39/> 39) 0.01 0.02
   Alcohol consumption (regularly/occasionally) 0.09 0.05
   Vegetable intake (usually/sometimes) 0.05 0.02
VOCs   
   Benzene 0.01 0.001
   Toluene 0.14 0.004
   Ethylbenzene 0.01 0.001
   M+P-Xylene 0.002 < 0.001
   O-Xylene 0.003 < 0.001
   1, 2,4 Trimethylebenzene 0.02 < 0.001
   Undecane 0.05 < 0.001
   Trichloroethylene 0.07 0.05
   Tetrachloroethylene 0.01 0.19
   Styrene 0.09 0.002
   Decane 0.001 < 0.001
   1,4 Dichlorobenzene 0.06 0.02
PAHs   
   Benzo(a)pyrene 0.40 0.35
   Anthracene 0.02 0.17
   Benz(a)anthracene 0.20 0.20
   Benzo(b)fluoranthene 0.16 0.22
   Benzo(g,h,i)perylene 0.09 0.22
   Benzo(k)fluornathene 0.21 0.24
   Chrysene 0.01 0.03
   Dibenz(a,h)anthracene 0.02 0.51
   Fluoranthene 0.04 0.06
   Indeno(1,2,3-cd)pyrene 0.08 0.20
   Phenanthrene 0.01 0.03
   Pyrene 0.03 0.11
   Benzo(j)fluoranthene 0.06 0.26
   Total [B(a)P]eq 0.15 0.34
  1. Total [B(a)p]eq, total Benzo(a)pyrene equivalent concentration
  2. MNi, micronuclei
  3. BNed; binucleated cells