|
Endothelial Marker
|
Number of participants
|
% change (95% CI)
|
Unadjusted p-value For interaction
|
Adjusted p-value
|
|---|
|
sICAM-1 homozygous carriers
|
31
|
-9.0 (-15.0, -2.5)
|
0.0002*
|
0.004*
|
|
Wild-type and heterozygotes
|
686
|
3.4 (1.9, 4. 9)
| | |
|
sVCAM-1 homozygous carriers
|
31
|
-9.2 (-17.2,-0.5)
|
0.005
|
0.1
|
|
Wild-type and heterozygotes
|
686
|
2.8 (0.9, 4.8)
| | |
- †IQR change in7 day moving average of PM2.5 = 4.27 μg/m3
- *models adjusted for education (≤12 years, 13-16 years, >16 years), ≥2 alcoholic drinks per day, age at first adhesion molecule measurement, time since first measurement, body mass index (BMI), diabetes diagnosi or fasting glucose >126 mg/dL, smoking status, pack-years smoked, hypertension medication use (yes/no), statin use, apparent temperature, seasonality (sine and cosine of month), CRP >10 mg/L.
