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Table 4 Results for rs1062923-PM2.5 interactions 7 day moving averages†

From: Ambient pollutants, polymorphisms associated with microRNA processing and adhesion molecules: the Normative Aging Study

Endothelial Marker Number of participants % change (95% CI) Unadjusted p-value For interaction Adjusted p-value
sICAM-1 homozygous carriers 31 -9.0 (-15.0, -2.5) 0.0002* 0.004*
Wild-type and heterozygotes 686 3.4 (1.9, 4. 9)   
sVCAM-1 homozygous carriers 31 -9.2 (-17.2,-0.5) 0.005 0.1
Wild-type and heterozygotes 686 2.8 (0.9, 4.8)   
  1. †IQR change in7 day moving average of PM2.5 = 4.27 μg/m3
  2. *models adjusted for education (≤12 years, 13-16 years, >16 years), ≥2 alcoholic drinks per day, age at first adhesion molecule measurement, time since first measurement, body mass index (BMI), diabetes diagnosi or fasting glucose >126 mg/dL, smoking status, pack-years smoked, hypertension medication use (yes/no), statin use, apparent temperature, seasonality (sine and cosine of month), CRP >10 mg/L.