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Table 4 Association between breast cancer and any exposure to PCE (ever/never)

From: Risk of breast cancer following exposure to tetrachloroethylene-contaminated drinking water in Cape Cod, Massachusetts: reanalysis of a case-control study using a modified exposure assessment

Prior Analysis

  

Latency period (years)

Crude OR (95% CI)

Adjusted OR (95% CI)

0

1.3 (1.0-1.6)

1.1 (0.9-1.4)

5

1.4 (1.1-1.8)

1.2 (0.9-1.5)

7

1.4 (1.1-1.8)

1.1 (0.8-1.5)

9

1.5 (1.1-2.0)

1.2 (0.9-1.6)

11

1.5 (1.1-2.1)

1.1 (0.8-1.6)

13

1.8 (1.3-2.7)

1.3 (0.9-2.0)

15

1.8 (1.2-2.9)

1.3 (0.8-2.1)

17

1.5 (0.8-2.7)

1.0 (0.5-1.9)

19

1.5 (0.6-3.7)

1.1 (0.4-2.9)

Current analysis

  

Latency period (years)

Crude OR (95% CI)

Adjusted OR (95% CI)

0

1.0 (0.8-1.1)

1.0 (0.8-1.2)

5

1.0 (0.8-1.2)

1.0 (0.8-1.2)

7

1.0 (0.9-1.2)

1.0 (0.9-1.3)

9

1.0 (0.8-1.2)

1.0 (0.8-1.2)

11

1.0 (0.9-1.3)

1.0 (0.8-1.2)

13

1.0 (0.8-1.3)

1.0 (0.8-1.2)

15

1.1 (0.9-1.4)

1.0 (0.8-1.2)

17

1.3 (1.0-1.6)

1.0 (0.7-1.3)

19

1.4 (0.9-2.1)

1.0 (0.7-1.4)

  1. Note: Referent group in the prior analysis was comprised of never exposed cases (n = 739) and controls (n = 1,085). The referent group in the current analysis was comprised of never exposed cases (n = 471) and controls (n = 645). Both adjusted analyses controlled for age at diagnosis or index year, vital status at interview, family history of breast cancer, personal history of breast cancer (before current diagnosis or index year), age at first live birth or stillbirth, occupational exposure to PCE, and study of origin.
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Environmental Health

ISSN: 1476-069X