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Table 1 Bias in estimation of the mean exposure magnitude, μ

From: Estimating equations for biomarker based exposure estimation under non-steady-state conditions

 

Exposure Frequency

       

Sample Size

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

2

0.033

0.024

-0.021

-0.008

-0.007

-0.003

-0.002

0.005

0

4

0.002

-0.007

0.017

-0.002

0.006

0.007

0.002

0.004

-0.005

8

0.01

0.004

-0.004

0.013

-0.001

-0.001

0.001

0.003

-0.001

16

0.008

-0.001

0.003

0.007

0

0

0.001

0.001

-0.001

32

0.001

0.004

0.003

0.007

-0.001

0.003

0.001

0.002

-0.001

64

0.007

0.004

0.003

0.005

-0.003

0

0

0.001

-0.001

128

0.005

0.004

0.002

0.007

-0.002

0.001

0

0.001

-0.001

256

0.006

0.003

0.001

0.005

-0.001

0.001

0.001

0.001

-0.001

512

0.004

0.001

0.002

0.007

-0.002

0.001

0.001

0.001

-0.001

1024

0.004

0.002

0.002

0.007

-0.002

0

0

0.001

0