Skip to main content

Table 4 Association of log-transformed HbA1c, FPI and HOMA-IR with log-transformed concentrations of iAs in drinking water and of iAs metabolites in urine, adjusted for age, sex, obesity and hypertension

From: Exposure to arsenic in drinking water is associated with increased prevalence of diabetes: a cross-sectional study in the Zimapán and Lagunera regions in Mexico

  HbA1c    FPI HOMA-IR
  βa 95% CI pb βa 95% CI pb βa 95% CI pb
Water iAs 0.193 0.018 0.369 0.03 -2.084 -2.720 -1.448 < 0.01 -1.641 -2.358 -0.924 < 0.01
Urinary tAs 0.164 -0.570 0.898 0.66 -5.313 -8.068 -2.559 < 0.01 -4.538 -7.514 -1.562 < 0.01
Urinary iAsIII -0.003 -0.075 0.069 0.94 -0.534 -0.803 -0.266 < 0.01 -0.409 -0.698 -0.121 < 0.01
Urinary MAsIII 0.003 -0.031 0.078 0.39 -0.037 -0.608 -0.007 0.02 -0.020 -0.053 0.013 0.25
Urinary DMAsIII 0.023 -0.031 0.078 0.40 -0.404 -0.608 -0.199 < 0.01 -0.301 -0.523 -0.078 < 0.01
Urinary iAsV 0.008 -0.005 0.021 0.23 -0.028 -0.079 0.023 0.29 -0.041 -0.096 0.014 0.14
Urinary MAsV 0.007 -0.086 0.100 0.88 -0.421 -0.777 -0.065 0.02 -0.292 -0.670 0.087 0.13
Urinary DMAsV 0.085 -0.281 0.452 0.65 -1.282 -2.689 0.125 0.07 -0.884 -2.382 0.615 0.25
Urinary DMAs/MAs ratio 0.074 -0.043 0.192 0.22 -0.403 -0.856 0.050 0.08 -0.372 -0.859 0.114 0.13
Urinary
MAs/iAs ratio
0.007 -0.016 0.030 0.56 0.092 0.003 0.182 0.04 0.123 0.030 0.216 0.01
  1. Abbreviations: HbA1c, glycated hemoglobin; FPI, fasting plasma insulin; HOMA-IR, homeostasis model assessment - insulin resistance; β, regression coefficient; CI, confidence interval.
  2. a Units of β and CI are 10 ppb for iAs concentration. Coefficients for metabolites are standardized to an increment of one inter-quartile range.
  3. b p-value for test of β = 0.