Figure 10

A graphic representation (current referred to as a cyclo-plot) of the multiple defects detected in the genome of a tumor (a small-cell lung cancer cell line) by deep sequencing. Individual chromosomes are depicted on the outer circle followed by concentric tracks for point mutation, copy number and rearrangement data relative to mapping position in the genome. Arrows indicate examples of the various types of somatic mutation present in this cancer genome. From Stratton et al., 2009 (ref. 29).