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Table 3 The principles and theory of population genetics can be applied to populations of cells.

From: Erratum to: Somatic mutations in cancer development

Events/processes

In populations of organisms

In populations of somatic cells

Mutation

Creates a mutant individual/family

Creates a mutant cell/clone

Lethal mutation

No offspring

No clonal growth

Neutral mutation

No visible change

No visible change

Mutation with absolute advantage

Mutant people will gradually take over

Clone will grow faster than other cells

Mutation with conditional advantage

Mutant people will increase in a certain environment

Clone will grow faster under certain conditions