Skip to main content

Table 2 Relationships between four phthalate metabolites and markers of obesity in women

From: Serum concentrations of phthalate metabolites are related to abdominal fat distribution two years later in elderly women

   MEHP MEP   MiBP MMP
Variable n Beta (95% CI) p-value Beta (95% CI) p-value Beta (95% CI) p-value Beta (95% CI) p-value
BMI (kg/m2) 479 0.10 (-0.20-0.41) 0.51 0.008 (-0.67-0.69) 0.98 0.39 (0.002-0.79) 0.049 0.28 (-0.095-0.66) 0.14
Waist (cm) 474 0.34 (-0.39-1.1) 0.36 -0.80 (-2.4-0.81) 0.33 1.3 (0.425-2.3) 0.0043 0.98 (0.090-1.9) 0.031
Waist/hip ratio 474 0.002 (-0.002-0.006) 0.24 -0.008 (-0.016-0.001) 0.086 0.004 (0.000-0.009) 0.079 0.005 (0.000-0.009) 0.051
DXA total fat (kg) 431 468 (-159-1096) 0.14 -469 (-1877-938) 0.51 1079 (283-1875) 0.0082 705 (-74-1484) 0.077
DXA leg fat (kg) 431 163 (-73-399) 0.18 -165 (-694-363) 0.54 275 (-25-576) 0.0733 115 (-179-409) 0.44
DXA trunk fat (kg) 431 206 (-127-539) 0.23 -187 (-934-559) 0.62 699 (279-1120) 0.0012 546 (135-958) 0.0096
DXA trunk/leg ratio 431 -0.007 (-0.033-0.019) 0.60 -0.004 (-0.062-0.054) 0.88 0.039 (0.006-0.072) 0.021 0.043 (0.011-0.075) 0.0082
MRI SAT (cm2) 135 4.8 (-10-20) 0.53 12 (-24-48) 0.51 52 (24-81) 0.0004 27 (3.1-52) 0.029
MRI VAT (cm2) 135 4.1 (-2.2-10) 0.20 3.6 (-11-19) 0.63 14 (1.4-26) 0.031 6.9 (-3.4-17) 0.19
MRI VAT/SAT ratio 135 0.005 (-0.018-0.028) 0.67 -0.001 (-0.056-0.054) 0.96 -0.018 (-0.064-0.028) 0.45 -0.019 (-0.057-0.019) 0.34
  1. Shown are results from linear regression models adjusting for serum cholesterol and triglycerides, education, exercise and smoking. The number of subjects used in the models for the different obesity outcome measurements are given as n. The units for the different obesity measures are given in table 1. The phthalate metabolites are given in ng/ml and ln-transformed values are used in the analysis
  2. BMI-Body mass index; DXA-Dual-energy X-ray absorptiometry; MEHP-Mono-(2-ethylhexyl) phthalate; MEP-Mono-ethyl phthalate; MiBP-Mono-isobutyl phthalate; MMP-Mono-methyl phthalate; MRI-Magnetic resonance imaging; SAT-Subcutaneous adipose tissue; VAT-Visceral adipose tissue