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Table 3 Relationships between four phthalate metabolites and markers of obesity in men

From: Serum concentrations of phthalate metabolites are related to abdominal fat distribution two years later in elderly women

  MEHP   MEP   MiBP MMP
Variable n Beta(95% CI) p-value Beta (95% CI) p-value Beta (95% CI) p-value Beta (95% CI) p-value
BMI (kg/m2) 482 -0.034 (-0.26-0.19) 0.77 0.31 (-0.097-0.72) 0.14 -0.083 (-0.35-0.19) 0.55 0.33 (0.051-0.61) 0.021
Waist (cm) 478 -0.27 (-0.91-0.37) 0.41 0.73 (-0.45-1.9) 0.22 -0.025 (-0.80-0.75) 0.95 0.97 (0.17-1.78) 0.0175
Waist/hip ratio 478 -0.004 (-0.008-0.0) 0.044 0.005 (-0.003-0.012) 0.22 0.001 (-0.004-0.005) 0.81 0.006 (0.001-0.011) 0.024
DXA total fat (kg) 410 12 (-527-552) 0.96 269 (-776-1315) 0.61 -73 (-754-608) 0.83 365 (-340-1071) 0.31
DXA leg fat (kg) 410 -24 (-200-152) 0.79 46 (-296-388) 0.79 -44 (-266-179) 0.70 37 (-194-268) 0.75
DXA trunk fat (kg) 410 0.56 (-332-333) 0.9974 347 (-297-991) 0.29 -23 (-443-398) 0.92 235 (-201-670) 0.29
DXA trunk/leg ratio 410 -0.008 (-0.048-0.033) 0.71 0.095 (0.018-0.17) 0.016 0.007 (-0.044-0.058) 0.78 0.021 (-0.031-0.074) 0.43
MRI SAT (cm2) 144 0.44 (-9.6-10) 0.93 9.2 (-10-29) 0.36 -11 (-34-12) 0.34 5.4 (-7.9-19) 0.43
MRI VAT (cm2) 144 3.3 (-4.9-11) 0.43 16 (0.49-32) 0.045 -5.9 (-24-13) 0.54 5.2 (-5.7-16) 0.35
MRI VAT/SAT ratio 144 0.002 (-0.032-0.036) 0.91 0.052 (-0.013-0.12) 0.12 0.001 (-0.076-0.079) 0.98 0.003 (-0.043-0.048) 0.91
  1. Shown are results from linear regression models adjusting for serum cholesterol and triglycerides, education, exercise and smoking. The number of subjects used in the models for the different obesity outcome measurements are given as n. The units for the different obesity measures are given in table 1. The phthalate metabolites are given in ng/ml and ln-transformed values are used in the analysis
  2. BMI-Body mass index; DXA-Dual-energy X-ray absorptiometry; MEHP-Mono-(2-ethylhexyl) phthalate; MEP-Mono-ethyl phthalate; MiBP-Mono-isobutyl phthalate; MMP-Mono-methyl phthalate; MRI-Magnetic resonance imaging; SAT-Subcutaneous adipose tissue; VAT-Visceral adipose tissue