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Table 2 Levels of organochloride residues (ng/g lipid) detected in serum samples in healthy women and in women diagnosed from breast cancer

From: Complex organochlorine pesticide mixtures as determinant factor for breast cancer risk: a population-based case–control study in the Canary Islands (Spain)

 

Healthy women (n =103)

Breast cancer women (n =121)

 
 

Mean ± SD

Median (p5-p95)

D (%)

Mean ± SD

Median (p5-p95)

D (%)

P

Lindane

24.7 ± 43.0

0.0

(0.0-111.4)

28 (27.2%)

53.2 ± 88.8

0.0

(0.0-220.0)

33 (27.3%)

n.s.a

n.s.b

Aldrin

27.1 ± 37.9

0.0

(0.0-100.1)

39 (37.9%)

72.5 ± 107.2

75.8

(0.0-116.4)

90 (74.4%)

<0.001a

<0.001b

Dieldrin

9.5 ± 16.4

0.0

(0.0-46.2)

33 (32.0%)

12.6 ± 29.5

0.0

(0.0-72.0)

27 (22.3%)

n.s.a

n.s.b

Endrin

231.4 ± 444.4

29.1

(0.0-1279.0)

60 (58.3%)

-

-

0 (0%)

n.a.a

n.a.b

Total

Cyclodienes

268.1 ± 443.3

91.4

(0.0-1297.8)

81 (78.6%)

85.2 ± 117.7

79.9

(0.0-156.1)

95 (78.5%)

n.sa

0.027b

p,p-DDE

198.0 ± 207.5

167.7

(45.0-706.0)

92(89.3%)

357.4 ± 326.0

300.1

(106.1-653.3)

118 (97.5%)

0.012a

<0.001b

p,p-DDD

21.8 ± 131.2

0.0

(0.0-129.2)

6 (5.8%)

440.3 ± 412.7

551.1

(0.0-1108.2)

87 (71.9%)

<0.001a

<0.001b

p,p-DDT

319.5 ± 417.4

217.0

(0.0-1428.6)

77 (74.8%)

149.3 ± 111.7

153.0

(0.0-327.9)

88 (72.7%)

n.s.a

<0.001b

Total DDTs

880.8 ± 971.9

665.0

(69.1-3622.0)

103 (100%)

1049.6 ± 679.5

979.3

(159.2-2228.7)

121 (100%)

n.s.a

0.001b

Total OCPs

1173.6 ±1339.9

706.0

(242.7-5263.6)

103 (100%)

1188.1 ± 657.2

1112.8

(184.2-2375.9)

121 (100%)

n.s.a

0.001b

  1. Abbreviations: SD, standard deviation; D, detected compound; p5-p95, percentiles 5 and 95 of the distribution; n.s., non-significant; n.a., not applicable.
  2. a χ 2 test.
  3. b Mann–Whitney U-test.