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Table 3 Levels of organochloride residues (ng/g lipid) detected in serum samples in healthy women and in women diagnosed from breast cancer older than 45 years old

From: Complex organochlorine pesticide mixtures as determinant factor for breast cancer risk: a population-based case–control study in the Canary Islands (Spain)

 

Healthy women (n = 49)

Breast cancer women (n =105)

 
 

Mean ± SD

Median (p5-p95)

D (%)

Mean ± SD

Median (p5-p95)

D (%)

P

Lindane

16.6 ± 34.6

0.0

(0.0-104.5)

10 (20.4%)

49.5 ± 85.4

0.0

(0.0-215.2)

27 (25.7%)

n.s.a

n.s.b

Aldrin

15.0 ± 27.5

0.0

(0.0-73.2)

12 (24.5%)

71.7 ± 114.3

74.8

(0.0-115.7)

76 (72.4%)

<0.001 a

<0.001 b

Dieldrin

7.0 ± 16.0

0.0

(0.0-49.7)

10 (20.4%)

12.2 ± 30.0

0.0

(0.0-71.7)

22 (21.0%)

n.s.a

n.s.b

Endrin

234.2 ± 466.0

0.0

(0.0-1553.1)

24 (49.0%)

-

-

0 (0%)

n.a.a

n.a.b

Total

Cyclodienes

256.1 ± 463.6

46.5

(0.0-1553.1)

33 (67.3%)

83.9 ± 125.2

77.5

(0.0-156.7)

80 (76.2%)

n.s.a

n.s.b

p,p-DDE

275.6 ± 266.2

220.8.7

(0.0-653.1)

46 (93.9%)

354.5 ± 327.3

303.8

(106.1-648.8)

102 (97.1%)

n.s.a

0.003b

p,p-DDD

8.6 ± 38.3

0.0

(0.0-94.3)

3 (6.1%)

412.4 ± 412.1

126.5.1

(0.0-1094.7)

72 (68.6%)

<0.001a

<0.001b

p,p-DDT

324.8 ± 395.5

205.4

(0.0-1334.6)

40 (81.6%)

153.2 ± 114.0

158.7

(0.0-327.3)

76 (72.4%)

n.s.a

0.008b

Total DDTs

937.3 ± 824.2

706.0

(133.2-3017.4)

49 (100%)

1022.7 ± 684.7

892.7

(143.0-2225.8)

105 (100%)

n.s.a

n.s.b

Total OCPs

1210.1 ± 1243.6

729.7

(267.9-4570.5)

49 (100%)

1156.0 ± 661.1

1057.3

(181.7-2364.8)

105 (100%)

n.s.a

0.043b

  1. Abbreviations: SD, standard deviation; D, detected compound; p5-p95, percentiles 5 and 95 of the distribution; n.s., non-significant; n.a., not applicable.
  2. a χ 2 test.
  3. b Mann–Whitney U-test.