Table 3 Risk of glioma and estimated cumulative pesticide exposure by type and target among participants with or without estimated exposures in the Upper Midwest Health Study

Pesticide Including proxy respondents   Excluding proxy respondents
Type and Target Cases (n = 798) Controls (n = 1,175)   Cases (n = 438) Controls (n = 1,141)
na Exposureb n Exposure ORc (95 % CI) n Exposure n Exposure OR (95 % CI)
Insecticide 128 177 (355) 261 155 (263) 0.99 (0.96, 1.02) 73 139 (265) 255 156 (265) 0.99 (0.94, 1.04)
Animal 89 117 (211) 175 118 (179) 0.97 (0.91, 1.03) 48 106 (156) 171 119 (181) 0.98 (0.90, 1.07)
Crops 78 156 (329) 145 135 (228) 1.00 (0.95, 1.04) 42 120 (290) 140 137 (232) 0.99 (0.92, 1.06)
Buildings/Lots 65 1.96 (5.39) 130 1.99 (5.42) 0.99 (0.96, 1.02) 32 1.05 (1.75) 125 2.05 (5.52) 0.95 (0.88, 1.04)
Herbicide 89 149 (255) 163 212 (344) 0.96 (0.91, 1.00) 53 110 (198) 160 214 (347) 0.94 (0.88, 1.01)
Fungicide 17 69.0 (89.5) 32 97.5 (164) 0.90 (0.72, 1.13) 12 76.3 (92.1) 32 97.5 (164) 0.98 (0.78, 1.23)
1. aNumber of participants with exposure estimated by an industrial hygienist. All other study participants are assigned zero exposure.
2. bMean (and standard deviation) of lifetime cumulative exposure in gram-years (g-years) for participants with estimated exposure. Cumulative exposure is calculated as 1,000 times the product of intensity (mg/hr) by decade, number of hours per day (hr/day), number of days per year (days/yr), and years by decade, and then summed across all decades.
3. cOdds ratio (and 95 % confidence intervals) of lifetime cumulative exposure (per 0.5 g for buildings/lots or per 50 g for all others based on median exposure), adjusted for matching variables (10-year age group, sex) and for age, and education.