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Table 5 Risk of glioma and estimated cumulative pesticide exposure by category among participants with or without estimated exposures in the Upper Midwest Health Study

From: The upper midwest health study: a case–control study of pesticide applicators and risk of glioma

Pesticide Including proxy respondents   Excluding proxy respondents  
Category Cases (n = 798) Controls (n = 1,175)   Cases (n = 438) Controls (n = 1,141)  
  na Exposureb n Exposure ORc (95 % CI) n Exposure n Exposure OR (95 % CI)
Arsenicals 15 4.86 (6.55) 36 49.5 (80.9) 0.95 (0.90, 1.00) 9 3.08 (2.18) 34 51.1 (82.8) 0.95 (0.86, 1.03)
Benzoic Acid 29 42.6 (72.6) 55 52.9 (73.4) 0.97 (0.92, 1.03) 16 23.6 (27.4) 54 53.8 (73.7) 0.91 (0.80, 1.04)
Carbamates 34 56.7 (125) 65 43.2 (86.9) 1.00 (0.97, 1.04) 20 55.1 (146) 64 43.8 (87.4) 1.00 (0.96, 1.04)
Chloroacetanilides 39 47.7 (72.1) 69 44.1 (60.0) 0.99 (0.94, 1.04) 19 54.8 (82.4) 67 45.4 (60.4) 0.99 (0.93, 1.06)
Dinitroanilines 29 19.1 (28.8) 47 28.8 (58.5) 0.99 (0.98, 1.01) 16 18.1 (32.0) 46 29.5 (59.0) 0.99 (0.98, 1.01)
Organochlorines 63 88.1 (143) 150 83.1 (145) 0.99 (0.97, 1.01) 31 86.4 (153) 146 83.8 (146) 0.99 (0.96, 1.01)
Organophosphates 66 96.5 (204) 145 81.3 (242) 1.00 (0.98, 1.01) 41 75.2 (219) 141 83.5 (245) 1.00 (0.98, 1.02)
Phenoxys 57 47.6 (83.7) 112 101 (170) 0.96 (0.93, 0.99)* 37 35.3 (54.3) 111 102 (170) 0.96 (0.92, 1.01)
Triazines 52 59.6 (86.8) 105 91.8 (194) 0.97 (0.95, 1.00) 27 56.3 (82.4) 103 93.5 (196) 0.97 (0.93, 1.01)
  1. aNumber of participants with exposure estimated by an industrial hygienist. All other study participants are assigned zero exposure.
  2. bMean (and standard deviation) of lifetime cumulative exposure in gram-years (g-years) for participants with estimated exposure. Cumulative exposure is calculated as 1,000 times the product of intensity (mg/hr) by decade, number of hours per day (hr/day), number of days per year (days/yr), and years by decade, and then summed across all decades.
  3. cOdds ratio (and 95 % confidence intervals) of lifetime cumulative exposure (per 1 g for arsenical and dinitroaniline, or per 10 g for all others based on median exposure), adjusted for matching variables (10-year age group, sex) and for age, and education.
  4. *p < 0.05.