Table 6 Common haplotypes in the As3MT gene and bladder cancer by average level of arsenic from drinking water
All Subjects | *As ≤3.72 μg/L | As >3.72 μg/L | |||||||
|---|---|---|---|---|---|---|---|---|---|
Haplotype** | Cases (%) | Controls (%) | OR‡† (95% CI) | Cases (%) | Controls (%) | OR (95% CI) | Cases (%) | Controls (%) | OR (95% CI |
T-T-G-T-A | 57.5 | 58.3 | 1.00 | 58.1 | 55.2 | 1.00 | 55.4 | 67.5 | 1.00 |
C-G-C-T-G | 22.0 | 22.7 | 0.97 (0.71 – 1.34) | 20.8 | 24.3 | 0.78 (0.53 – 1.13) | 25.4 | 17.9 | 1.92 (0.98 – 3.76) |
T-G-C-C-G | 11.1 | 9.3 | 1.20 (0.78 – 1.84) | 9.9 | 11.0 | 0.86 (0.52 – 1.41) | 14.5 | 4.4 | 3.90 (1.39 – 10.9) |
C-T-C-T-A | 6.0 | 5.5 | 1.14 (0.64 – 2.01) | 7.1 | 5.3 | 1.42 (0.75 – 2.69) | 2.8 | 6.4 | 0.54 (0.13 – 2.22) |