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Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for the prevalence of hyperthyroidism associated with estimated nitrate levels in residential wells

From: Modeled nitrate levels in well water supplies and prevalence of abnormal thyroid conditions among the Old Order Amish in Pennsylvania

Overall    Men   Women  
mg/L nitrate-nitrogen Cases OR 95%CI Cases OR 95%CI Cases OR 95%CI
Clinical Hyperthyroidism
   Low nitrate (< 6.5) 5 1.0 1 1.0 4 1.0
   High nitrate (= > 6.5) 5 0.95 (0.27-3.28) 2 1.85(0.17-20.7) 3 0.70 (0.16-3.15)
Subclinical Hyperthyroidism
   Low nitrate (< 6.5) 13 1.0 5 1.0 8 1.0
   High nitrate (= > 6.5) 12 0.86(0.39-1.91) 3 0.57 (0.13-2.38) 9 1.07 (0.41-2.79)
Subclinical Hyperthyroidism
   Q1 [0.34-4.46] 6 1.0 1 1.0 5 1.0
   Q2 [4.47-6.53] 7 1.14 (0.38-3.42) 4 4.01(0.45-36.2) 3 0.53 (0.14-2.47)
   Q3 [6.54-8.55] 8 1.29 (0.45-3.76) 2 1.98 (0.18-22.0) 6 1.17 (0.35-3.90)
   Q4 [8.56-16.4] 4 0.62 (0.18-2.23) 1 0.99 (0.06-15.9) 3 0.56 (0.13-2.38)
p-trend   0.36   0.25   0.65
  1. Models adjusted for age and BMI; model with men and women combined is also adjusted for gender