|
Tumor receptor status
|
ER+/PR+
|
ER+/PR-
|
ER-
|
|---|
|
N cases (total=1006)
|
538
|
157
|
188
|
|
Model 1 – Cumulative exposure,
1
no interactions
|
| |
OR (95% CI) Wald P (two-tailed)
|
|
Farming
|
1.32 (0.94-1.85) 0.12
|
1.35 (0.73-2.49)
|
1.71 (1.12-2.62) 0.014
|
|
Metalworking
|
2.03 (1.11-3.71) 0.022
|
1.73 (0.77-3.89)
|
1.02 (0.36-2.89)
|
|
Bars, gambling
|
3.87 (1.39-10.8) 0.010
|
3.24 (0.44-24.1)
|
0.15 (0.00-4.27)
|
|
Auto industry: plastics
|
3.63 (1.90-6.94) 9×10-5
|
1.17 (0.28-4.97)
|
1.76 (0.78-3.94)
|
|
Canning
|
1.50 (0.55-4.10)
|
4.01 (1.37-11.8) 0.011
|
3.19 (1.16-8.75) 0.024
|
|
Model 2 – Cumulative exposure with prior farm interaction terms (IpAg)
|
| |
OR (95% CI) Wald P (two-tailed)
|
|
Farming
|
1.32 (0.93-1.87)
|
1.34 (0.70-2.57)
|
1.76 (1.13-2.74) 0.012
|
|
Metalworking
|
2.21 (1.14-4.30) 0.019
|
1.51 (0.65-3.50)
|
1.17 (0.43-3.13)
|
|
Metalworking … IpAg
|
0.84 (0.53-1.32)
|
1.26 (0.95-1.67) 0.11
|
0.47 (0.12-1.93)
|
|
Bars, gambling
|
2.87 (0.93-8.84) 0.066
|
2.78 (0.35-22.1)
|
0.20 (0.01-5.45)
|
|
Bars, gambling … IpAg
|
3.03 (0.74-12.4) 0.12
|
3.46 (0.27-45.0)
|
0.00 (0.00->100)
|
|
Auto industry: plastics
|
3.13 (1.62-6.05) 7×10-4
|
1.26 (0.30-5.32)
|
0.96 (0.31-2.99)
|
|
Auto plastics… IpAg
|
2.10 (0.52-8.43)
|
0.65 (0.03-15.3)
|
3.03 (0.80-11.6) 0.10
|
|
Canning
|
1.52 (0.51-4.51)
|
1.21 (0.26-5.60)
|
4.85 (1.25-18.8) 0.022
|
|
Canning… IpAg
|
0.91 (0.51-1.65)
|
1.81 (1.08-3.04) 0.025
|
0.62 (0.22-1.72)
|
- Odds ratios (OR) by conditional logistic regression with terms for reproductive, demographic risk factors as in Table 4 and terms for employment duration; matching on age in 3-year intervals; models include all major sector exposures; IpAg, interaction with farming: cumulative (sector rating × prior cum. exposure in agriculture); breast cancer cases not of the specified receptor type were excluded from analysis.
- OR for cumulative exposure evaluated at 10.0 year in high-exposed jobs (lagged 5 year) or, for interactions, at 10 years in high-exposed jobs and 1 year in prior high-exposed farm work.
