a) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
HBCD | Questions | VH | H | M | L | VL | No. Resp. | Mean | Std | CNS | RANK (CONS) |
5 | 4 | 3 | 2 | 1 | |||||||
Environmental Matrix | |||||||||||
EM03 | Sediments | 2 | 5 | 5 | 1 | 0 | 13 | 3.62 | 0.87 | 0.70 | 30 |
EM04 | Sewage sludge | 2 | 6 | 2 | 3 | 0 | 13 | 3.54 | 1.05 | 0.62 | 53 |
Main sources of exposure | |||||||||||
EX05 | Occupationally exposed | 4 | 2 | 6 | 1 | 0 | 13 | 3.69 | 1.03 | 0.62 | 57 |
Knowledge of the mechanisms of actions | |||||||||||
TX18 | a- HBCD | 0 | 2 | 1 | 10 | 5 | 18 | 2.00 | 0.91 | 0.75 | 10 |
TX19 | b-HBCD | 0 | 1 | 1 | 9 | 7 | 18 | 1.78 | 0.81 | 0.74 | 12 |
TX20 | g-HBCD | 0 | 1 | 2 | 10 | 5 | 18 | 1.94 | 0.80 | 0.77 | 5 |
TX21 | Other metabolites of HBCD | 0 | 0 | 1 | 7 | 10 | 18 | 1.50 | 0.62 | 0.78 | 3 |
(b) | |||||||||||
HBCD | Questions | VH | H | M | L | VL | No. Resp. | Mean | Std | CNS | RANK (CONS) |
5 | 4 | 3 | 2 | 1 | |||||||
Environmental Matrix | |||||||||||
EM01 | Debromination & biological halflives | 0 | 3 | 9 | 1 | 0 | 13 | 3.15 | 0.55 | 0.84 | 1 |
Occupational exposed | |||||||||||
EX11 | Inhalation | 3 | 2 | 5 | 3 | 0 | 13 | 3.38 | 1.12 | 0.59 | 63 |
EX12 | Ingestion | 1 | 3 | 4 | 4 | 1 | 13 | 2.92 | 1.12 | 0.62 | 58 |
Infants and children | |||||||||||
EX14 | Inhalation | 1 | 1 | 4 | 5 | 2 | 13 | 2.54 | 1.13 | 0.60 | 61 |
EX16 | Via food | 0 | 3 | 5 | 2 | 3 | 13 | 2.62 | 1.12 | 0.59 | 62 |
Toxicokinetics | |||||||||||
TK05 | Accumulating in the body | 0 | 6 | 9 | 3 | 0 | 18 | 3.17 | 0.71 | 0.77 | 4 |
TK06 | Excreted via bile and faeces | 0 | 5 | 8 | 5 | 0 | 18 | 3.00 | 0.77 | 0.77 | 6 |
TK08 | Distribution to different tissues | 0 | 5 | 12 | 1 | 0 | 18 | 3.22 | 0.55 | 0.83 | 2 |
Human Epidemiological studies | |||||||||||
Nervous system | |||||||||||
TX05 | Males exposed as adults | 1 | 2 | 3 | 9 | 3 | 18 | 2.39 | 1.09 | 0.62 | 59 |
TX06 | Females exposed as adults | 1 | 2 | 3 | 9 | 3 | 18 | 2.39 | 1.09 | 0.62 | 60 |