Skip to main content

Table 2 Characteristic of participants, stratified by cohort and dust exposure groups

From: Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study

 

Offspring

Third generation

Total

(n = 1247)

(n = 3538)

(n = 4785)

 

Less likely dust exposure

Highly likely dust exposure

Less likely dust exposure

Highly likely dust exposure

Less likely dust exposure

Highly likely dust exposure

 

(n = 1126)

(n = 121)

(n = 3112)

(n = 426)

(n = 4238)

(n = 547)

Male, n (%)

444 (39.43)

100 (82.64)

1298 (41.71)

378 (88.73)

1742 (41.10)

478 (87.39)

FEV1, L ± SD

2.71 ± 0.78

3.09 ± 0.75

3.54 ± 0.78

4.02 ± 0.71

3.32 ± 0.86

3.81 ± 0.82

FEV1/FVC, % ± SD

0.73 ± 0.07

0.72 ± 0.08

0.78 ± 0.06

0.77 ± 0.06

0.77 ± 0.07

0.76 ± 0.07

FEV1/FVC < 70%, n (%)

337 (29.93)

43 (35.54)

318 (10.22)

49 (11.50)

655 (15.46)

92 (16.82)

Age, years ± SD

62.83 ± 8.02

60.48 ± 7.87

39.81 ± 8.58

41.03 ± 8.57

45.93 ± 13.21

45.33 ± 11.66

Height, inches ± SD

65.81 ± 3.76

67.99 ± 3.46

66.90 ± 3.65

69.29 ± 2.98

66.61 ± 3.71

69.01 ± 3.14

Pack-years* ± SD

21.40 ± 21.58

30.73 ± 23.32

12.56 ± 13.61

19.12 ± 15.90

15.50 ± 17.19

22.07 ± 18.74

Smoking status, n (%)

Never smokers

501 (44.49)

36 (29.75)

1854 (59.58)

177 (41.55)

2355 (55.57)

213 (38.94)

Former smokers

522 (46.36)

58 (47.93)

789 (25.35)

115 (27.00)

1311 (30.93)

173 (31.63)

Current smokers

103 (9.15)

27 (22.31)

469 (15.07)

134 (31.46)

572 (13.50)

161 (29.43)

  1. *Pack-years mean and standard deviation calculated among current and former smokers.