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Table 3 Adjusted association measured between seafood consumption and wheeze, eczema and food allergy

From: Maternal fish and shellfish consumption and wheeze, eczema and food allergy at age two: a prospective cohort study in Brittany, France

   Probable wheeze Certain wheeze Eczema Food allergy
   OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Complete-case analysis     
Fish consumption* 1398 1395 1395
  <1 time a month 1 1 1 1
  1–4 times a month 0.83 (0.58-1.17) 0.69 (0.45-1.05)§ 1.06 (0.77-1.48) 1.27 (0.72-2.24)
  ≥2 times a week 1.04 (0.70-1.55) 0.90 (0.56-1.44) 0.89 (0.61-1.29) 1.48 (0.80-2.76)
Shellfish consumption*     
  <1 time a month 1 1 1 1
  ≥1 time a month 1.08 (0.83-1.40) 1.08 (0.78-1.49) 1.09 (0.85-1.40) 1.62 (1.11-2.37)‡
Fish consumption**     
  <1 time a month 1 1 1 1
  1–4 times a month 0.82 (0.57-1.17) 0.68 (0.45-1.04)§ 1.04 (0.75-1.45) 1.16 (0.65-2.07)
  ≥2 times a week 1.02 (0.68-1.54) 0.87 (0.54-1.42) 0.85 (0.58-1.25) 1.27 (0.67-2.39)
Shellfish consumption**     
  <1 time a month 1 1 1 1
  ≥1 time a month 1.06 (0.81-1.39) 1.08 (0.77-1.51) 1.13 (0.87-1.45) 1.57 (1.06-2.31)‡
Multiple imputation analysis    
Fish consumption** 2981 2981 2981
  <1 time a month 1 1 1 1
  1–4 times a month 0.90 (0.69-1.17) 0.86 (0.63-1.17) 1.03 (0.76-1.39) 1.13 (0.70-1.83)
  ≥2 times a week 1.07 (0.78-1.47) 1.11 (0.75-1.67) 0.92 (0.58-1.46) 1.37 (0.79-2.39)
Shellfish consumption**     
  <1 time a month 1 1 1 1
  ≥1 time a month 1.02 (0.80-1.31) 1.02 (0.81-1.30) 1.01 (0.76-1.34) 1.52 (1.05-2.21)‡
  1. *Adjusted for: mother’s age, maternal education, folic acid supplementation, familial history of asthma/allergy, child’s sex, small-for-gestational age, infant’s method of feeding, day care attendance, post-natal exposure to tobacco and, child’s age at follow-up.
  2. **Both fish and shellfish consumption were included in the model with the adjustment variables above.
  3. § p-value < 0.10; ‡ p-value < 0.05.