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Table 2 Arsenic metabolite proportions by participant characteristics

From: Body composition and arsenic metabolism: a cross-sectional analysis in the Strong Heart Study

Participants

N (%)

% iAs median (IQR)

P value

% MMA median (IQR)

P value

% DMA median (IQR)

P value

Overall

3,663

7.9 (5.6, 11.0)

 

13.9 (10.8, 17.5)

 

77.8 (72.0, 82.7)

 

Sex

       

  Female

2,157 (58. 9)

7.0 (5.0, 10.0)

 

13.0 (10.0, 16.0)

 

79.7 (74.7, 84.1)

 

  Male

1,506 (41.1)

9.4 (6.7, 12.9)

<0.001

15.7 (12.4, 19.4)

<0.001

74.5 (67.9, 80.0)

<0.001

Age

       

  < 55 years

1,836 (50.1)

8.5 (6.0, 11.5)

 

13.9 (10.8, 17.6)

 

77.3 (71.7, 82.2)

 

  ≥ 55 and < 65 years

1,190 (32.5)

7.6 (5.4, 10.5)

 

13.6 (10.7, 17.3)

 

78.6 (72.4, 83.3)

 

  ≥ 65 years

637 (17.4)

7.1 (5.0, 9.7)

<0.001

14.6 (11.2, 17.8)

0.03

78.2 (72.4, 82.7)

0.005

BMI

       

  < 25 kg/m2

557 (15.2)

9.1 (6.2, 12.4)

 

16.7 (13.2, 20.3)

 

74.4 (67.3, 79.6)

 

  ≥25 and < 30 kg/m2

1,236 (33.7)

8.4 (5.8, 11.5)

 

15.0 (11.6, 18.5)

 

76.3 (70.5, 81.3)

 

  ≥30 and < 35 kg/m2

1,057 (28.9)

7.5 (5.5, 10.5)

 

13.3 (10.5, 16.5)

 

78.9 (73.3, 83.3)

 

  ≥35 kg/m2

813 (22.2)

7.1 (5.2, 9.8)

<0.001

11.9 (9.1, 14.8)

<0.001

80.8 (75.9, 85.3)

<0.001

Study center

       

  Arizona

1,281 (35.0)

8.6 (6.1, 11.5)

 

13.3 (10.4, 16.4)

 

78.1 (72.6, 82.5)

 

  Oklahoma

1,141 (31.2)

6.6 (4.6, 9.3)

 

13.4 (10.2, 16.7)

 

79.6 (74.0, 84.3)

 

  North or South Dakota

1,241 (33.9)

8.4 (6.1, 11.7)

<0.001

15.3 (11.9, 19.2)

<0.001

75.9 (69.6, 81.1)

<0.001

Smoking status

       

  Never

1,177 (32.1)

7.4 (5.3, 10.1)

 

13.3 (10.1, 16.3)

 

79.0 (73.9, 83.5)

 

  Former

1,240 (33.9)

7.6 (5.4, 10.5)

 

13.6 (10.8, 17.1)

 

78.4 (72.8, 83.2)

 

  Current

1,246 (34.0)

9.0 (6.1, 12.2)

<0.001

15.2 (11.6, 19.0)

<0.001

75.8 (69.2, 81.3)

<0.001

Drinking status

       

  Never

575 (15.7)

7.1 (5.2, 9.8)

 

13.5 (10.6, 16.6)

 

79.2 (73.6, 83.3)

 

  Former

1,517 (41.4)

7.6 (5.4, 10.8)

 

13.9 (10.8, 17.3)

 

78.1 (72.4, 83.0)

 

  Current

1,571 (42.9)

8.4 (5.9, 11.7)

<0.001

14.2 (10.8, 18.0)

0.008

77.0 (70.8, 82.2)

<0.001

High school completion

       

  Yes

1,793 (47.5)

7.7 (5.5, 10.8)

 

13.9 (10.7, 17.3)

 

78.0 (72.3, 83.0)

 

  No

1,924 (52.5)

8.3 (5.7, 11.2)

0.002

13.9 (10.8, 17.7)

0.28

77.6 (71.7, 82.5)

0.03

  1. *P values are from Kruskal-Wallis tests.
  2. Arsenic % species must sum to 100% within each person.