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Table 3 Results of multiple linear regression analysis of association between natural log transformed serum concentrations of PCBs and chlorinated pesticides and lipid fractions (n = 575)

From: Analysis of the effects of exposure to polychlorinated biphenyls and chlorinated pesticides on serum lipid levels in residents of Anniston, Alabama

 

Total PCBs

Total pesticides

 

Model 1

Model 2

Model 1

Model 2

 

β

0.05

0.03

0.07

0.06

Total lipids

p-value

<0.0001

0.0433

<0.0001

0.0001

 

SP R22

0.0280

0.0063

0.0447

0.0230

 

β

0.03

0.02

0.04

0.03

Total Cholesterol

p-value

0.0090

0.1816

0.0017

0.0277

 

SP R22

0.0112

0.0029

0.0162

0.0079

 

β

0.00

0.01

−0.01

−0.01

HDL cholesterol

p-value

0.9685

0.7388

0.5714

0.5122

 

SP R22

0.0000

0.0002

0.0005

0.0002

 

β

0.03

0.02

0.03

0.02

LDL cholesterol

p-value

0.1233

0.3382

0.1209

0.3301

 

SP R22

0.0041

0.0016

0.0041

0.0016

 

β

0.10

0.05

0.15

0.12

Triglycerides

p-value

0.0007

0.1365

<0.0001

0.0007

 

SP R22

0.0178

0.0034

0.0321

0.0177

  1. Multiple linear regression models to assess the associations between serum total concentrations of PCBs and pesticides with serum total concentrations of lipids and its fractions after adjustment.
  2. Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but results for total PCBs are not adjusted for total pesticides and results for total pesticides are not adjusted for total PCBs.
  3. Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but with additional adjustment for total PCBs for the pesticide results and for total pesticides for the PCB results.
  4. SP R22 – Type II semi-partial R2.