Analysis of the effects of exposure to polychlorinated biphenyls and chlorinated pesticides on serum lipid levels in residents of Anniston, Alabama

Table 5 Results of multiple linear regression analysis of association between natural log transformed serum concentrations of groups of PCB congeners based on the number of total chlorines and the various lipid fractions (n = 575)

		Tri- and tetra chloro		Penta-chloro		Hexa-chloro		Hepta-chloro		Octa-, nona-, and deca-chloro
		Model 1	Model 2	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2
Total lipids	β	0.06	0.08	0.03	−0.06	0.04	0.02	0.05	−0.04	0.06	0.08
	p-value	<0.0001	0.0008	0.0081	0.0653	0.0004	0.7883	<0.0001	0.5873	<0.0001	0.0055
	SP R²2	0.0318	0.0172	0.0114	0.0052	0.0199	0.0001	0.0302	0.0004	0.0480	0.0118
Total cholesterol	β	0.04	0.07	0.02	−0.06	0.02	0.04	0.03	−0.06	0.04	0.07
	p-value	0.0019	0.0041	0.1332	0.0715	0.0308	0.5659	0.0063	0.4051	0.0002	0.0229
	SP R²2	0.0157	0.0132	0.0037	0.0052	0.0077	0.0005	0.0122	0.0011	0.0224	0.0083
HDL cholesterol	β	0.01	0.02	0.06	0.02	0.00	−0.08	0.00	0.09	−0.01	−0.05
	p-value	0.5381	0.6441	0.6625	0.5902	0.9262	0.3807	0.9658	0.3222	0.6741	0.2344
	SP R²2	0.0006	0.0003	0.0002	0.0004	0.0000	0.0012	0.0000	0.0015	0.0003	0.0021
LDL cholesterol	β	0.03	0.06	0.01	−0.08	0.02	0.11	0.03	−0.15	0.04	0.11
	p-value	0.1333	0.1304	0.5504	0.1407	0.2239	0.2837	0.112	0.1432	0.0080	0.1432
	SP R²2	0.0039	0.0039	0.0006	0.0037	0.0025	0.0019	0.0043	0.0036	0.0060	0.0110
Triglycerides	β	0.11	0.14	0.05	−0.07	0.08	−0.11	0.11	0.02	0.14	0.19
Triglycerides	p-value	0.0008	0.0284	0.0458	0.4191	0.0077	0.5383	0.0004	0.9287	<0.0001	0.0130
	SP R²2	0.0174	0.0072	0.0062	0.0010	0.0111	0.0006	0.0197	0.0000	0.0350	0.0093

Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but not adjusted for the remaining PCB groups and chlorinated pesticides.
Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, and adjusted for the all remaining PCB groups and chlorinated pesticides.
SP R²2 – Type II semi-partial R².

ISSN: 1476-069X