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Table 5 Results of multiple linear regression analysis of association between natural log transformed serum concentrations of groups of PCB congeners based on the number of total chlorines and the various lipid fractions (n = 575)

From: Analysis of the effects of exposure to polychlorinated biphenyls and chlorinated pesticides on serum lipid levels in residents of Anniston, Alabama

  Tri- and tetra chloro Penta-chloro Hexa-chloro Hepta-chloro Octa-, nona-, and deca-chloro
  Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
Total lipids β 0.06 0.08 0.03 −0.06 0.04 0.02 0.05 −0.04 0.06 0.08
p-value <0.0001 0.0008 0.0081 0.0653 0.0004 0.7883 <0.0001 0.5873 <0.0001 0.0055
SP R22 0.0318 0.0172 0.0114 0.0052 0.0199 0.0001 0.0302 0.0004 0.0480 0.0118
Total cholesterol β 0.04 0.07 0.02 −0.06 0.02 0.04 0.03 −0.06 0.04 0.07
p-value 0.0019 0.0041 0.1332 0.0715 0.0308 0.5659 0.0063 0.4051 0.0002 0.0229
SP R22 0.0157 0.0132 0.0037 0.0052 0.0077 0.0005 0.0122 0.0011 0.0224 0.0083
HDL cholesterol β 0.01 0.02 0.06 0.02 0.00 −0.08 0.00 0.09 −0.01 −0.05
p-value 0.5381 0.6441 0.6625 0.5902 0.9262 0.3807 0.9658 0.3222 0.6741 0.2344
SP R22 0.0006 0.0003 0.0002 0.0004 0.0000 0.0012 0.0000 0.0015 0.0003 0.0021
LDL cholesterol β 0.03 0.06 0.01 −0.08 0.02 0.11 0.03 −0.15 0.04 0.11
p-value 0.1333 0.1304 0.5504 0.1407 0.2239 0.2837 0.112 0.1432 0.0080 0.1432
SP R22 0.0039 0.0039 0.0006 0.0037 0.0025 0.0019 0.0043 0.0036 0.0060 0.0110
Triglycerides β 0.11 0.14 0.05 −0.07 0.08 −0.11 0.11 0.02 0.14 0.19
p-value 0.0008 0.0284 0.0458 0.4191 0.0077 0.5383 0.0004 0.9287 <0.0001 0.0130
  SP R22 0.0174 0.0072 0.0062 0.0010 0.0111 0.0006 0.0197 0.0000 0.0350 0.0093
  1. Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but not adjusted for the remaining PCB groups and chlorinated pesticides.
  2. Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, and adjusted for the all remaining PCB groups and chlorinated pesticides.
  3. SP R22 – Type II semi-partial R2.