Analysis of the effects of exposure to polychlorinated biphenyls and chlorinated pesticides on serum lipid levels in residents of Anniston, Alabama

Table 7 Results of multiple linear regression analysis of the associations between natural log transformed serum concentrations of the various pesticides or pesticide groups and the various lipid fractions (n = 575)

		DDT		Chlordane		Mirex		HCB		HCCH
		Model 1	Model 2	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2
Total lipids	β	0.05	0.00	0.11	0.05	0.05	0.02	0.21	0.21	0.07	−0.03
	p-value	<0.0001	0.8109	<0.0001	0.0037	0.0002	0.2608	<0.0001	<0.0001	<0.0001	0.1205
	SP R²2	0.0300	0.0000	0.0875	0.0110	0.0226	0.0016	0.1539	0.0805	0.0438	0.0031
Total Cholesterol	β	0.03	0.00	0.06	0.02	0.03	0.01	0.15	0.18	0.04	−0.04
	p-value	0.0124	0.9873	<0.0001	0.3877	0.0125	0.3697	<0.0001	<0.0001	0.0018	0.0629
	SP R²2	0.0103	0.0000	0.0313	0.0011	0.0102	0.0012	0.0880	0.0653	0.0160	0.0052
HDL cholesterol	β	−0.01	0.00	−0.03	−0.03	0.01	0.02	−0.06	−0.08	−0.01	0.02
	p-value	0.5831	0.9323	0.1309	0.3034	0.7112	0.4401	0.0205	0.0267	0.4439	0.5214
	SP R²2	0.0005	0.0000	0.0035	0.0016	0.0002	0.0009	0.0080	0.0074	0.0009	0.0006
LDL cholesterol	β	0.02	0.00	0.05	−0.00	0.02	0.00	0.17	0.25	0.03	−0.07
	p-value	0.2229	0.9100	0.0266	0.9531	0.2846	0.8392	<0.0001	<0.0001	0.1862	0.0198
	SP R²2	0.0026	0.0000	0.0085	0.0000	0.0020	0.0001	0.0525	0.0577	0.0030	0.0088
Triglycerides	β	0.10	−0.01	0.26	0.18	0.09	0.01	0.44	0.39	0.18	−0.02
Triglycerides	p-value	0.0003	0.8396	<0.0001	<0.0001	0.0054	0.8391	<0.0001	<0.0001	<0.0001	0.6926
	SP R²2	0.0206	0.0000	0.0833	0.0212	0.0121	0.0001	0.1059	0.0422	0.0391	0.0002

Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but not adjusted for the remaining pesticides and PCBs.
Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, and adjusted for all remaining pesticides and PCBs.
SP R²2 – Type II semi-partial R².

ISSN: 1476-069X