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Table 7 Results of multiple linear regression analysis of the associations between natural log transformed serum concentrations of the various pesticides or pesticide groups and the various lipid fractions (n = 575)

From: Analysis of the effects of exposure to polychlorinated biphenyls and chlorinated pesticides on serum lipid levels in residents of Anniston, Alabama

  DDT Chlordane Mirex HCB HCCH
  Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
Total lipids β 0.05 0.00 0.11 0.05 0.05 0.02 0.21 0.21 0.07 −0.03
p-value <0.0001 0.8109 <0.0001 0.0037 0.0002 0.2608 <0.0001 <0.0001 <0.0001 0.1205
SP R22 0.0300 0.0000 0.0875 0.0110 0.0226 0.0016 0.1539 0.0805 0.0438 0.0031
Total Cholesterol β 0.03 0.00 0.06 0.02 0.03 0.01 0.15 0.18 0.04 −0.04
p-value 0.0124 0.9873 <0.0001 0.3877 0.0125 0.3697 <0.0001 <0.0001 0.0018 0.0629
SP R22 0.0103 0.0000 0.0313 0.0011 0.0102 0.0012 0.0880 0.0653 0.0160 0.0052
HDL cholesterol β −0.01 0.00 −0.03 −0.03 0.01 0.02 −0.06 −0.08 −0.01 0.02
p-value 0.5831 0.9323 0.1309 0.3034 0.7112 0.4401 0.0205 0.0267 0.4439 0.5214
SP R22 0.0005 0.0000 0.0035 0.0016 0.0002 0.0009 0.0080 0.0074 0.0009 0.0006
LDL cholesterol β 0.02 0.00 0.05 −0.00 0.02 0.00 0.17 0.25 0.03 −0.07
p-value 0.2229 0.9100 0.0266 0.9531 0.2846 0.8392 <0.0001 <0.0001 0.1862 0.0198
SP R22 0.0026 0.0000 0.0085 0.0000 0.0020 0.0001 0.0525 0.0577 0.0030 0.0088
Triglycerides β 0.10 −0.01 0.26 0.18 0.09 0.01 0.44 0.39 0.18 −0.02
p-value 0.0003 0.8396 <0.0001 <0.0001 0.0054 0.8391 <0.0001 <0.0001 <0.0001 0.6926
  SP R22 0.0206 0.0000 0.0833 0.0212 0.0121 0.0001 0.1059 0.0422 0.0391 0.0002
  1. Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but not adjusted for the remaining pesticides and PCBs.
  2. Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, and adjusted for all remaining pesticides and PCBs.
  3. SP R22 – Type II semi-partial R2.