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Table 5 Percent change (95% confidence interval) in microvascular function comparing active to sham filtration and corresponding to a 10 μg/m 3 decrease in PM 2.5 in the bedroom, estimated by mixed-effects models adjusted for BMI, age and gender and stratified according to medication

From: An indoor air filtration study in homes of elderly: cardiovascular and respiratory effects of exposure to particulate matter

Medication Active versus sham filter Per 10 μg/m3decrease in PM2.5in the bedroom
Medication No medication Medication No medication
Vasoactive (n = 11) −3.7 (−13.4, 7.0) −0.7 (−5.6, 4.5) −2.3 (−14.7, 11.8) 7.7 (2.3, 13.3)*
Statins (n = 11) −0.8 (−8.8, 8.0) −1.6 (−6.8, 3.9) 1.5 (−9.0, 13.3) 7.7 (1.1, 14.6)*
Cyclooxygenase inhibitors (n = 12) −5.0 (−11.0, 1.5) −0.1 (−5.7, 5.8) 4.2 (−2.1, 10.9) 7.8 (0.5, 15.5)*
Any drug (n = 23) −3.17 (−8.8, 2.8) 0.37 (−6.4, 7.7) 3.3 (−3.9, 11.9) 8.4 (2.0, 15.1)*
  1. *P < 0.05.