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Table 2 The association between a doubling in BC concentration and total cognitive z-score by HFE polymorphisms

From: Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study

  Expected difference in total cognitive z-scorea (95% confidence interval) p-value for interaction
HFE C282Y
   Wild Type −0.061 (-0.115, -0.007) 0.11
   Variant 0.073 (-0.081, 0.228)  
HFE H63D
   Wild Type −0.071 (-0.132, -0.009) 0.64
   Variant −0.024 (-0.131, 0.082)  
  1. Abbreviations: HFE, hemochromatosis gene; BC, black carbon.
  2. aAdjusted for age, education, first language, computer experience, physical activity, alcohol consumption, diabetes, dark fish consumption, percentage of residential census tract that is nonwhite, percentage of residential census tract adults with a college degree, indicator for first cognitive assessment, and indicator for part-time resident.