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Table 3 The association between a doubling in BC concentration and low MMSE scores by HFE polymorphisms

From: Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study

 

Odds ratioa (95% confidence interval)

p-value for interaction

HFE C282Y

   Wild Type

1.37 (1.08, 1.73)

0.20

   Variant

0.91 (0.50, 1.64)

 

HFE H63D

   Wild Type

1.24 (0.97, 1.59)

0.22

   Variant

1.74 (1.06, 2.87)

 
  1. Abbreviations: HFE, hemochromatosis gene; MMSE, Mini-Mental State Examination; BC, black carbon.
  2. aAdjusted for age, education, first language, computer experience, physical activity, alcohol consumption, diabetes, dark fish consumption, percentage of residential census tract that is nonwhite, percentage of residential census tract adults with a college degree, indicator for first cognitive assessment, and indicator for part-time resident.
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Environmental Health

ISSN: 1476-069X