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Table 4 Proximity to any facility, the average annual dioxin emission index, and risk of non-Hodgkin Lymphoma: all NHL and by histological subtype

From: Residential proximity to industrial combustion facilities and risk of non-Hodgkin lymphoma: a case–control study

  Never lived within distance Ever lived within distance Average annual emission index
Quartile 1 Quartile 2 Quartile 3 Quartile 4
  Cases Controls OR (95%CI)a Cases Controls OR (95%CI)a Cases Controls OR (95%CI)a Cases Controls OR (95%CI)a Cases Controls OR (95%CI)a Cases Controls OR (95%CI)a
5 km                   
All NHL 595 459 1.0 374 290 1.0 (0.8-1.2) 97 73 1.0 (0.7-1.4) 102 72 1.1 (0.7-1.5) 85 73 0.9 (0.6-1.3) 90 72 1.0 (0.7-1.4)
DLBCL 182 459 1.0 122 290 1.0 (0.7-1.3) 30 73 1.0 (0.6-1.6) 28 72 0.9 (0.5-1.5) 32 73 1.0 (0.6-1.6) 32 72 1.0 (0.6-1.7)
Follicular 141 459 1.0 86 290 1.0 (0.7-1.4) 22 73 0.9 (0.5-1.6) 26 72 1.1 (0.7-1.9) 18 73 0.8 (0.4-1.5) 20 72 1.0 (0.5-1.7)
CLL/SLL 66 459 1.0 36 290 0.8 (0.5-1.3) 9 73 0.9 (0.4-2.0) 8 72 0.7 (0.3-1.6) 9 73 0.8 (0.3-1.7) 10 72 0.9 (0.4-1.9)
Marginal zone 57 459 1.0 25 290 1.1 (0.6-1.8) 5 73 0.5 (0.2-1.5) 10 72 1.5 (0.7-3.3) 2 73 0.5 (0.1-2.2) 8 72 2.6 (1.0-6.8)
Other subtypes 78 459 1.0 50 290 0.8 (0.5-1.3) 15 73 1.2 (0.6-2.3) 12 72 0.8 (0.4-1.6) 13 73 0.7 (0.3-1.5) 10 72 0.5 (0.2-1.2)
NOS lymphoma 71 459 1.0 55 290 1.4 (0.9-2.2) 16 73 1.4 (0.8-2.7) 18 72 1.8 (1.0-3.3) 11 73 1.1 (0.5-2.4) 10 72 1.1 (0.5-2.5)
3 km                   
All NHL 754 579 1.0 215 170 1.0 (0.8-1.3) 67 43 1.2 (0.8-1.8) 39 42 0.7 (0.5-1.2) 52 43 0.9 (0.6-1.4) 57 42 1.1 (0.7-1.7)
DLBCL 235 579 1.0 69 170 0.9 (0.6-1.3) 22 43 1.2 (0.7-2.1) 11 42 0.6 (0.3-1.2) 14 43 0.7 (0.4-1.3) 22 42 1.2 (0.7-2.1)
Follicular 178 579 1.0 49 170 1.0 (0.6-1.4) 18 43 1.3 (0.7-2.5) 6 42 0.5 (0.2-1.1) 11 43 0.8 (0.4-1.7) 14 42 1.1 (0.6-2.2)
CLL/SLL 81 579 1.0 21 170 0.9 (0.5-1.6) 3 43 0.6 (0.2-1.9) 4 42 0.7 (0.2-2.0) 9 43 1.7 (0.7-3.7) 5 42 0.8 (0.3-2.3)
Marginal zone 66 579 1.0 16 170 1.3 (0.7-2.4) 3 43 0.7 (0.2-2.3) 4 42 1.3 (0.4-3.9) 3 43 1.1 (0.3-4.0) 6 42 3.0 (1.1-8.3)
Other subtypes 101 579 1.0 27 170 0.8 (0.5-1.3) 8 43 1.0 (0.5-2.3) 8 42 1.0 (0.4-2.2) 6 43 0.6 (0.3-1.6) 5 42 0.6 (0.3-2.5)
NOS lymphoma 93 579 1.0 33 170 1.5 (0.9-2.3) 13 43 2.1 (1.1-4.2) 6 42 1.1 (0.4-2.7) 9 43 1.5 (0.6-3.2) 5 42 0.9 (0.3-2.5)
  1. DLBCL = Diffuse large B-cell lymphoma; CLL/SLL = Chronic lymphocytic leukemia/small lymphocytic lymphoma; NOS lymphoma = not otherwise specified.
  2. a Adjusted for age (<35, 35–44, 45–54, 55–64, >65 yrs), gender, race (white, black, other/unknown), center (Detroit, Seattle, Iowa, Los Angeles), years of education (<12, 12–15, >16).