Figure 5
XEs cause cell proliferation, and XE mixtures disrupt cell proliferation evoked by E 2 . Increasing concentrations of XEs (10-15 M – 10-7 M) compared to increasing concentrations of E2 (10-15 M-10-7 M) alone (A) were assessed after a 3-day growth period. Mixtures of E2 with XEs were assessed in B. Cell number was measured by the CV assay and compared to vehicle (V)-treated cells (n = 24 over 3 experiments). All error bars represent S.E M. The width of the vehicle bar represents a S. E. of ± 1.3. * = p < 0.05 compared to vehicle; in B, # = p < 0.05 compared to 10-9 M E2.