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Table 4 Association between PM 2.5 exposure across the work shift (mg/m 3 ) and methylation of Alu , LINE-1 and iNOS measured in whole blood collected post-shift

From: A panel study of occupational exposure to fine particulate matter and changes in DNA methylation over a single workday and years worked in boilermaker welders

  

Unadjusted regression1

 

Adjusted regression2

 

N

ß

SE

p-value

N

ß

SE

p-value

Global DNA Methylation

        

 Alu (%5mC)

37

0.02

0.07

0.73

35

0.05

0.07

0.47

 LINE-1 (%5mC)

37

-0.05

0.10

0.61

35

-0.12

0.10

0.28

Gene specific DNA Methylation

        

 iNOS (%5mC)

29

0.22

0.10

0.04

27

0.25

0.11

0.04

  1. 1 Adjusted for DNA methylation in the sample pre-shift.
  2. 2 Adjusted for DNA methylation in the sample pre-shift, currently smoking (yes), age, and wearing a respirator.