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Table 2 Quartiles of sperm PAH-DNA adducts in relation to semen parameters and sperm DNA fragmentation (n = 433)

From: Bulky DNA adducts in human sperm associated with semen parameters and sperm DNA fragmentation in infertile men: a cross-sectional study

Variables

Sperm PAH-DNA adducts

P for trendb

Tertile 1

Tertile 2

Tertile 3

Tertile 4

 

(n = 108)

(n = 108)

(n = 109)

(n = 108)

 

Semen quality parameters

     

Seminal volume (ml)

3.84 ± 1.67

3.53 ± 1.52

3.73 ± 1.47

3.80 ± 1.63

0.697

Concentration (106/ml)a

4.14 ± 0.89

3.78 ± 1.08*

3.70 ± 1.14*

3.37 ± 1.44*

<0.001

Sperm count (106/ml)a

5.31 ± 1.04

5.03 ± 1.16

4.90 ± 1.24

4.35 ± 1.57*

<0.001

Motility (% motile)

52.35 ± 25.22

47.22 ± 27.44

47.98 ± 19.03

41.16 ± 22.56*

0.004

CASA motion parameters

     

  VSL (μm/s)

36.63 ± 12.49

35.46 ± 10.30

35.24 ± 7.50

33.88 ± 9.90

0.057

  VCL (μm/s)

44.38 ± 18.33

42.95 ± 10.62

42.97 ± 11.71

35.85 ± 7.45*

<0.001

  LIN (%)

58.88 ± 10.96

57.01 ± 12.28

59.48 ± 9.84

55.74 ± 14.26

0.234

DNA Fragmentation (%) a

2.34 ± 0.95

2.37 ± 0.99

2.56 ± 1.04

2.84 ± 1.01*

<0.001

  1. aln-transformed.
  2. bAdjusted for age, smoking, alcohol drinking, BMI and abstinence time.
  3. *P <0.05 compared with the lowest sperm PAH-DNA adducts tertile (Tertile 1).