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Table 4 Standardized mortality ratios (SMRs), underlying cause of death

From: Evaluation of mortality among marines and navy personnel exposed to contaminated drinking water at USMC base Camp Lejeune: a retrospective cohort study

Underlying Camp Pendleton (reference) Camp Lejeune
Cause of death Obs. Exp. SMR (95% CI) Obs. Exp. SMR (95% CI)
All causes 9,365 10,922 0.86 (0.84, 0.87) 8,964 10,864 0.83 (0.81, 0.84)
All cancers 1,008 1,296 0.78 (0.73, 0.83) 1,078 1,272 0.85 (0.80, 0.90)
Diseases of primary interest
Kidney cancer 33 37.20 0.89 (0.61, 1.25) 42 36.08 1.16 (0.84, 1.57)
Bladder cancer 14 13.65 1.03 (0.56, 1.72) 11 13.04 0.84 (0.42, 1.51)
Liver* cancer 39 69.21 0.56 (0.40, 0.77) 51 69.20 0.74 (0.55, 0.97)
Esophageal cancer 27 43.33 0.62 (0.41, 0.91) 35 41.34 0.85 (0.59, 1.18)
Hematopoietic cancers 167 215.93 0.77 (0.66, 0.90) 165 211.10 0.78 (0.67, 0.91)
Hodgkin 23 25.86 0.89 (0.56, 1.33) 24 25.03 0.96 (0.61, 1.43)
NHL** 68 87.56 0.78 (0.60, 0.98) 58 85.50 0.68 (0.52, 0.88)
Multiple myeloma 12 16.26 0.74 (0.38, 1.29) 17 16.13 1.05 (0.61, 1.69)
Leukemias 64 86.26 0.74 (0.57, 0.95) 66 84.43 0.78 (0.60, 0.99)
Cervical cancer 2 3.53 0.57 (0.07, 2.05) 5 4.88 1.03 (0.33, 2.39)
Diseases of secondary interest
Pancreatic cancer 44 60.05 0.73 (0.53, 0.98) 57 58.29 0.98 (0.74, 1.27)
Colon cancer 73 93.28 0.78 (0.61, 0.98) 86 92.29 0.93 (0.75, 1.15)
Rectal cancer 16 29.84 0.54 (0.31, 0.87) 24 29.54 0.81 (0.52, 1.21)
Soft tissue cancers 21 27.82 0.75 (0.47, 1.15) 29 27.44 1.06 (0.71, 1.52)
Brain cancer 80 93.36 0.86 (0.68, 1.07) 74 88.95 0.83 (0.65, 1.04)
Laryngeal cancer 13 12.15 1.07 (0.57, 1.83) 6 11.92 0.50 (0.18, 1.10)
Lung*** cancer 216 265.44 0.81 (0.71, 0.93) 237 259.01 0.92 (0.80, 1.04)
Oral cancers**** 35 37.64 0.93 (0.65, 1.29) 26 37.38 0.70 (0.45, 1.02)
Breast (female) cancer 7 14.68 0.48 (0.19, 0.98) 10 19.62 0.51 (0.24, 0.94)
Prostate cancer 15 10.68 1.41 (0.79, 2.32) 18 10.41 1.73 (1.02, 2.73)
Liver diseases 233 322.70 0.72 (0.63, 0.82) 191 311.90 0.61 (0.53, 0.71)
Kidney diseases 37 71.72 0.52 (0.37, 0.71) 37 74.54 0.50 (0.35, 0.68)
ALS 27 19.42 1.39 (0.92, 2.02) 21 18.45 1.14 (0.70, 1.74)
Multiple sclerosis 10 14.95 0.67 (0.32, 1.23) 12 14.75 0.81 (0.42, 1.42)
Smoking-related diseases (not known to be related to solvent exposure)
Stomach cancer 29 41.43 0.70 (0.47, 1.01) 35 41.88 0.84 (0.58, 1.16)
Cardiovascular disease† 1,376 1,791 0.77 (0.73, 0.81) 1,390 1,781 0.78 (0.74, 0.82)
COPD 45 55.82 0.81 (0.59, 1.08) 47 53.89 0.87 (0.64, 1.16)
  1. Not evaluated due to small numbers were Parkinson’s disease and male breast cancer.
  2. *Biliary passages, liver and gall bladder **Non-Hodgkin lymphoma.
  3. ***Trachea, bronchus, and lung ****Oral cavity and Pharynx.
  4. †Includes diseases of the heart and other diseases of the circulatory system.
  5. Camp Lejeune = 154,932; person-years = 4,140,042.
  6. Camp Pendleton = 154,969; person-years = 4,190,132.