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Figure 3 | Environmental Health

Figure 3

From: Chemicals having estrogenic activity can be released from some bisphenol a-free, hard and clear, thermoplastic resins

Figure 3

EA (%RME2) of three Tritan™ BPA-replacement resins. Each individual value is the maximum %RME2 that is the mean of 3–4 intra-assay data points for a single assay run on different wells of the same plate (see Methods). The mean (M) and SD (S) values of EA for a given type of assay in a single cell of the table is given when ≥8 independent assays were performed for that given assay condition, i.e., for the cell representing Tritan, MCF-7 assay, saline extract, UVA stress. If no assays were run for the conditions associated with a cell in Figure 2, no EA values are given for that cell, i.e., the cell is blank. Many more assays were performed on Tritan™ EX401 plaques, MCF-7 assay, saline extyract UVA stress compasred to other resins because Tritan™ EX401 resin was used as a positive control in various assays for EA. When eight our more individual assays were performed for the variables associated with a given cell, the number of independent assays (n), their mean (M) and their standard deviation (S) are indicated. Yellow highlighted cells, or combination of cells, indicate that at least 3 assays were consistently positive for EA (i.e., exhibited EA significantly greater (p <0.01, Student’s T-test, %RME2 ≥ 15) than VC and SC values (see Methods). A yellow-highlighted resin (e.g., all Tritans resins tested) indicates a resin for which at least one cell or combination of cells exhibited EA. **%RME2 values for 58 MCF-7 assays of Tritan™ EX401 stressed by UVC and extracted by saline: 146, 114, 112, 103, 99, 97, 93, 93, 92, 91, 91, 90, 90, 90, 88, 88, 88, 87, 86, 85, 85, 85, 80, 79, 72, 69, 69, 69, 69, 68, 67, 66, 66, 64, 64, 63, 58, 53, 53, 50, 49, 49, 47, 47, 45, 45, 45, 42, 41, 39. 39, 35, 16, 13, 9, 9, 8, 6.

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