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Table 3 Inflammatory markers before and 5 hours after exposure to filtered air, unfiltered diesel exhaust (DE) and diesel exhaust filtered by filter A and B

From: Assessment of the capacity of vehicle cabin air inlet filters to reduce diesel exhaust-induced symptoms in human volunteers

  Filtered air Unfiltered DE Diesel exhaust + filter A Diesel exhaust + filter B
(n = 28) (n = 28) (n = 28) (n = 28)
  Before 5 hours after Delta Before 5 hours after Delta Before 5 hours after Delta Before 5 hours after Delta
IL-6 0.60 0.68 -0.06 0.64 0.77 0.1 0.69 0.73 -0.03 0.65 0.69 0.04
pg/ml 0.38-0.96 0.43-1.01 -0.16-0.15 0.34-1.01 0.49-1.02 -0.09-0.3 0.64-0-97 0.54-1.04 -0.15-0.22 0.39-0.86 0.4-1.22 -0.19-0.26
TNF-α 0.69 0.55 -0.08 0.72 0.61 -0.02 0.88 0.91 -0.05 0.72 0.65 -0.11
pg/ml 0.48-0.93 0.25-0.86 -0.25-0.02 0.42-1.05 0.24-1.00 -0.25-0.05 0.55-1.24 0.39-1.09 -0.25-0.07 0.45-0.97 0.28-1.16 -0.19-0.08
p-selectin 69.8 64.7 -0.11 60.0 62.6 1.23 64.4 69.0 -1.98 66.6 66.6 2.52
ng/ml 54.4-80.1 56.7-74.2 -12.7-10.15 45.9-76.1 49.9-77.2 -3.88-10.0 55.9-86.7 54.8-74.1 -17.1-10.8 53.1-83.5 54.9-87.45 -17-4-8.6
s-ICAM-1 251 260 3.72 245 244 9.29 265 257 -0.93 298 297 -0.83
ng/ml 208-299 223-312 -16.7-58.5 193-278 214-297 -19.1-42.76 220-329 211-327 -42.4-18.9* 244-318 227-318 -30.1-22.8*
CD40L 246 268 29.86 270 244 -13.23 332 249 -11.36 316 251 -78.98
pg/ml 181-331 191-367 -70.8-96.1 173-379 182-320 -99.4-42.3 215-389 159-346 -122.7-48.1 179-434 135-359 -167.3-20.7
  1. Data were expressed as medians with inter-quartile range. Wilcoxon’s Signed-Rank test was used for evaluation of differences between delta changes (5 hours post minus pre exposure) across exposure to unfiltered DE and filter air, unfiltered DE and DE filtered with filter A and unfiltered DE with DE filtered with filter B (active charcoal containing filter). P values of < 0.05 were considered significant. *P < 0.05.