| |
Filtered air
|
Unfiltered DE
|
Diesel exhaust + filter A
|
Diesel exhaust + filter B
|
|---|
|
(n = 28)
|
(n = 28)
|
(n = 28)
|
(n = 28)
|
|---|
| |
Before
|
5 hours after
|
Delta
|
Before
|
5 hours after
|
Delta
|
Before
|
5 hours after
|
Delta
|
Before
|
5 hours after
|
Delta
|
|---|
|
IL-6
|
0.60
|
0.68
|
-0.06
|
0.64
|
0.77
|
0.1
|
0.69
|
0.73
|
-0.03
|
0.65
|
0.69
|
0.04
|
|
pg/ml
|
0.38-0.96
|
0.43-1.01
|
-0.16-0.15
|
0.34-1.01
|
0.49-1.02
|
-0.09-0.3
|
0.64-0-97
|
0.54-1.04
|
-0.15-0.22
|
0.39-0.86
|
0.4-1.22
|
-0.19-0.26
|
|
TNF-α
|
0.69
|
0.55
|
-0.08
|
0.72
|
0.61
|
-0.02
|
0.88
|
0.91
|
-0.05
|
0.72
|
0.65
|
-0.11
|
|
pg/ml
|
0.48-0.93
|
0.25-0.86
|
-0.25-0.02
|
0.42-1.05
|
0.24-1.00
|
-0.25-0.05
|
0.55-1.24
|
0.39-1.09
|
-0.25-0.07
|
0.45-0.97
|
0.28-1.16
|
-0.19-0.08
|
|
p-selectin
|
69.8
|
64.7
|
-0.11
|
60.0
|
62.6
|
1.23
|
64.4
|
69.0
|
-1.98
|
66.6
|
66.6
|
2.52
|
|
ng/ml
|
54.4-80.1
|
56.7-74.2
|
-12.7-10.15
|
45.9-76.1
|
49.9-77.2
|
-3.88-10.0
|
55.9-86.7
|
54.8-74.1
|
-17.1-10.8
|
53.1-83.5
|
54.9-87.45
|
-17-4-8.6
|
|
s-ICAM-1
|
251
|
260
|
3.72
|
245
|
244
|
9.29
|
265
|
257
|
-0.93
|
298
|
297
|
-0.83
|
|
ng/ml
|
208-299
|
223-312
|
-16.7-58.5
|
193-278
|
214-297
|
-19.1-42.76
|
220-329
|
211-327
|
-42.4-18.9*
|
244-318
|
227-318
|
-30.1-22.8*
|
|
CD40L
|
246
|
268
|
29.86
|
270
|
244
|
-13.23
|
332
|
249
|
-11.36
|
316
|
251
|
-78.98
|
|
pg/ml
|
181-331
|
191-367
|
-70.8-96.1
|
173-379
|
182-320
|
-99.4-42.3
|
215-389
|
159-346
|
-122.7-48.1
|
179-434
|
135-359
|
-167.3-20.7
|
- Data were expressed as medians with inter-quartile range. Wilcoxon’s Signed-Rank test was used for evaluation of differences between delta changes (5 hours post minus pre exposure) across exposure to unfiltered DE and filter air, unfiltered DE and DE filtered with filter A and unfiltered DE with DE filtered with filter B (active charcoal containing filter). P values of < 0.05 were considered significant. *P < 0.05.
