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Table 3 Hazard ratios for cancer and diabetes in the groups with different urinary findings in men

From: Mortality and causes of deaths of inhabitants with renal dysfunction induced by cadmium exposure of the polluted Jinzu River basin, Toyama, Japan; a 26-year follow-up

Cause of deaths

Control areas

Cd polluted areas

Pro(-) and Glu(-)

Pro(+) and/or Glu(+)

Pro(-) and Glu(-)

Pro(-) and Glu(+)

Pro(+) and Glu(-)

Pro(+) and Glu(+)

(N=748)

(N=178)

(N=2556)

(N=331)

(N=123)

(N=147)

D

HR

D

HR

(95% CI)

D

HR

(95% CI)

D

HR

(95% CI)

D

HR

(95% CI)

D

HR

(95% CI)

Malignant neoplasms

142

1.00

32

1.16

(0.79, 1.71)

522

1.05

(0.87, 1.27)

82

0.87

(0.66, 1.14)

26

0.97

(0.62, 1.51)

23

1.04

(0.66, 1.63)

  Esophagus

2

1.00

2

4.58

(0.64, 32.6)

20

2.63

(0.61, 11.3)

6

3.59

(0.70, 18.5)

1

2.94

(0.26, 32.8)

0

-

-

  Stomach

48

1.00

9

1.02

(0.50, 2.09)

142

0.88

(0.63, 1.25)

26

0.87

(0.53, 1.42)

6

0.66

(0.26, 1.68)

6

0.80

(0.34, 1.90)

  Colon, rectum

14

1.00

2

0.68

(0.15, 2.98)

53

1.01

(0.55, 1.82)

7

0.73

(0.29, 1.80)

2

0.85

(0.19, 3.78)

2

0.99

(0.22, 4.41)

  Liver

15

1.00

1

0.35

(0.05, 2.64)

42

0.82

(0.44, 1.51)

8

0.84

(0.35, 2.01)

5

2.27

(0.81, 6.36)

3

1.59

(0.45, 5.61)

  Gall bladder

6

1.00

1

0.93

(0.11, 7.70)

21

1.02

(0.41, 2.55)

4

1.01

(0.29, 3.60)

0

-

-

0

-

-

  Pancreas

7

1.00

2

1.76

(0.35, 8.71)

33

1.45

(0.60, 3.48)

6

1.40

(0.45, 4.35)

0

-

-

2

2.16

(0.42, 11.0)

  Lung

30

1.00

7

1.13

(0.50, 2.57)

121

1.08

(0.72, 1.62)

11

0.52

(0.26, 1.03)

5

0.84

(0.32, 2.18)

6

1.19

(0.49, 2.89)

  Prostate

3

1.00

2

3.81

(0.63, 22.9)

13

1.16

(0.33, 4.09)

5

2.32

(0.55, 9.74)

3

1.43

(0.15, 14.2)

0

-

-

  Bladder

3

1.00

0

-

-

11

1.03

(0.28, 3.72)

1

0.48

(0.05, 4.58)

1

1.87

(0.19, 18.3)

0

-

-

  Kidney and urinal tract

1

1.00

1

5.00

(0.31, 80.4)

5

1.23

(0.14, 11.1)

0

-

-

2

11.0

(0.96, 125)

1

4.39

(0.25, 76.9)

  Lymph, blood forming organs

6

1.00

0

-

-

24

1.13

(0.46, 2.78)

4

0.97

(0.27, 3.45)

1

1.05

(0.13, 8.82)

2

2.27

(0.44, 11.6)

Endocrine, nutritional and metabolic diseases

4

1.00

5

6.81

(1.82, 25.5)**

15

0.89

(0.29, 2.71)

11

3.42

(1.08, 10.8)*

0

-

-

4

5.80

(1.39, 24.2)*

  Diabetes

1

1.00

5

27.8

(3.23, 238)**

11

2.56

(0.33, 20.0)

11

13.4

(1.72, 105)*

0

-

-

4

23.3

(2.53, 214)**

  1. Pro(+): urinary protein ≥ 10 mg/dL, Pro(-): urinary protein <10 mg/dL, Glu(+): urinary glucose ≥ +/-, Glu(-): urinary glucose negative.
  2. N number of subjects, D number of deaths, HR Hazard ratio, CI confident interval.
  3. *P < 0.05, **P < 0.01 compared with Pro(-) and Glu(-) in controls.