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Table 1 Association between SNPs in the CYP2B6 gene and circulating lipid-normalized levels of BDE-47

From: Genetic variation in the CYP2B6 Gene is related to circulating 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study

SNPa position Minor allele/major allele MAFb nobsin the analysis Beta (95% CI) on natural logaritm scale P-value (Bonferroni-corrected p-value for significance = 0.0021)
rs1808682c 41489448 A/G 0.23 920 0.11 (0.026, 0.19) 9.5*10-3
rs3760657 41495433 G/A 0.12 924 0.16 (0.058, 0.27) 2.5*10-3
rs2099361 41498348 C/A 0.36 923 -0.18 (-0.25, -0.11) 2.8*10-7
rs2014141 41499989 A/G 0.41 924 -0.21 (-0.28, -0.14) 4.9*10-9
rs8192711 41500057 A/G 0.05 923 -0.12 (-0.27, 0.031) 0.12
rs8100458 41500213 C/T 0.35 924 0.17 (0.10, 0.24) 3.4*10-6
rs4803415 41500593 T/C 0.10 886 0.19 (0.08, 0.30) 6.9*10-4
rs8101756 41502522 C/T 0.24 923 0.062 (-0.018, 0.14) 0.13
rs16974799 41504077 T/C 0.24 924 0.062 (-0.018, 0.14) 0.13
rs4803417 41508020 C/A 0.41 924 -0.21 (-0.28, -0.14) 4.9*10-9
rs10500282 41508442 C/T 0.26 923 0.087 (0.009, 0.16) 0.028
rs11672911 41508744 A/G 0.32 924 0.17 (0.10, 0.25) 5.6*10-6
rs2279345 41515702 T/C 0.39 924 -0.17 (-0.24, -0.10) 9.6*10-7
rs8192718 41515814 A/G 0.02 924 -0.099 (-0.39, 0.19) 0.50
rs6508965 41517688 T/C 0.39 924 -0.17 (-0.24, -0.10) 1.1*10-6
rs8192719 41518773 T/C 0.24 924 0.066 (-0.012, 0.14) 0.10
rs11882450 41520142 G/A 0.06 924 -0.095 (-0.24, 0.052) 0.20
rs11673270 41520844 C/A 0.24 924 0.060 (-0.019, 0.14) 0.14
rs7260329 41521638 A/G 0.32 924 0.17 (0.093, 0.24) 9. 3*10-6
rs2291287 41522451 G/A 0.06 924 -0.095 (-0.24, 0.052) 0.20
rs1042389c 41524153 G/A 0.21 923 0.040 (-0.041, 0.12) 0.33
rs1552223 41525952 G/A 0.39 924 -0.16 (-0.23, -0.092) 5.0*10-6
rs2113103c 41528667 A/G 0.15 924 0.076 (-0.018, 0.17) 0.11
rs7255904c 41529020 A/G 0.45 921 0.13 (0.059, 0.19) 2.6*10-4
  1. aSNP = single nucleotide polymorphisms.
  2. bMAF = Minor allele frequency.
  3. cSNPs genotyped in Uppsala, others in Oxford.
  4. The position data originates from the UCSC Genome Browser on Human February 2009 (GRCh37/hg19) and allele data originates from the genotyped SNPs included in the study. All SNPs are located on chromosome 19.