Concentration-response curves for E2 and plastic extracts. Mean and SD data for concentration (g/mL or M) – response (%RME2) curves of luciferase activity in BG1Luc cells and MCF-7 cell proliferation by extracts of PC (A,B) or PC-replacement (C-I) products. Black lines and associated data points show agonist activity for all data points not associated with toxicity (see Methods). Red lines and associated data points show results of exposure of extracts to 10-8 M ICI. Horizontal dotted lines show 15%RME2 values that are significantly (p < 0.01) greater than the vehicle (VC) and sham (SC) controls. PC-replacement products. Panel C. Costar 3300 tissue culture plate. D. Cup.1: Camelbak kids reusable water bottle, blue; Cup 2: Nalgene kids reusable water bottle, blue. E. Cup.1: Camelbak kids reusable water bottle, blue; Cup 2: Nalgene kids reusable water bottle, blue. F. Zeonor COP bottle. Topas COC bottle. G. AVENT baby bottle, green; Crate and Barrel wine glass, green. H. Born Free baby bottle A; Green to Grow baby bottle B. I. Dr. Weil baby bottle; Contigo reusable water bottle, turquoise.