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Table 3 Associations between placenta OTCs and weight/length gain across OTC categories in weighted linear regression a

From: Association of placenta organotin concentrations with growth and ponderal index in 110 newborn boys from Finland during the first 18 months of life: a cohort study

Organotin compound

Conc. (ng/g fw)

Weight gain 0–3 months

 

Weight gain 3–18 months

 
  

N

Weight gain (kg/week)

β (95% CI)

p

N

Weight gain (kg/week)

β (95% CI)

p

DBT

<0.10

31

0.220

ref

 

27

0.087

ref

 
 

0.10–0.14

30

0.222

0.016 (−0.011, 0.044)

0.23

26

0.082

−0.007 (−0.020, 0.006)

0.29

 

≥0.15

41

0.230

0.021 (0.000, 0.043)

0.054

33

0.079

−0.009 (−0.020, 0.002)

0.11

TBT

<0.10

31

0.224

ref

 

26

0.086

ref

 
 

0.10–0.4

39

0.217

0.005 (−0.018, 0.029)

0.64

34

0.084

−0.007 (−0.022, 0.008)

0.36

 

>0.4

32

0.235

0.024 (0.003, 0.044)

0.024

26

0.078

−0.011 (−0.024, 0.003)

0.12

TPhT

<0.02

60

0.227

ref

 

49

0.080

ref

 
 

≥0.02

42

0.220

0.005 (−0.016, 0.027)

0.62

37

0.085

0.002 (−0.008, 0.011)

0.74

Sum of OTCs

<0.25

26

0.220

ref

 

22

0.083

ref

 
 

0.25–0.50

31

0.228

0.025 (−0.002, 0.052)

0.065

27

0.086

<0.001 (−0.016, 0.016)

1.00

 

>0.50

45

0.225

0.018 (−0.001, 0.037)

0.062

37

0.080

−0.008 (−0.021, 0.005)

0.21

Organotin compound

Conc. (ng/g fw)

Length gain 0–3 monhts

 

Length gain 3–18 monhts

 
  

N

Length gain (cm/week)

β (95% CI)

p

N

Length gain (cm/week)

β (95% CI)

p

DBT

<0.10

32

0.83

ref

 

28

0.34

ref

 
 

0.10–0.14

30

0.83

0.054 (−0.038, 0.146)

0.25

26

0.33

−0.014 (−0.039, 0.010)

0.25

 

≥0.15

41

0.83

0.047 (−0.021, 0.114)

0.18

33

0.33

−0.008 (−0.027, 0.011)

0.42

TBT

<0.10

32

0.82

ref

 

27

0.34

ref

 
 

0.10–0.4

39

0.83

−0.015 (−0.085, 0.055)

0.67

34

0.33

−0.025 (−0.048, −0.001)

0.042

 

>0.4

32

0.84

0.024 (−0.038, 0.085)

0.45

26

0.34

−0.014 (−0.036, 0.009)

0.22

TPhT

<0.02

60

0.83

ref

 

49

0.34

ref

 
 

≥0.02

43

0.83

−0.005 (−0.061, 0.051)

0.86

38

0.34

−0.006 (−0.025, 0.013)

0.54

Sum of OTCs

<0.25

27

0.84

ref

 

23

0.34

ref

 
 

0.25–0.50

31

0.82

0.012 (−0.084, 0.108)

0.81

27

0.34

−0.012 (−0.042, 0.018)

0.41

 

>0.50

45

0.83

0.018 (−0.039, 0.076)

0.53

37

0.33

−0.012 (−0.035, 0.010)

0.29

  1. aAdjusted for maternal age at birth, maternal pregnancy body mass index, diabetes (yes/no) and smoking (yes/no) during pregnancy, and infant weight for gestational age.