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Table 3 Associations between placenta OTCs and weight/length gain across OTC categories in weighted linear regression a

From: Association of placenta organotin concentrations with growth and ponderal index in 110 newborn boys from Finland during the first 18 months of life: a cohort study

Organotin compound Conc. (ng/g fw) Weight gain 0–3 months   Weight gain 3–18 months  
   N Weight gain (kg/week) β (95% CI) p N Weight gain (kg/week) β (95% CI) p
DBT <0.10 31 0.220 ref   27 0.087 ref  
  0.10–0.14 30 0.222 0.016 (−0.011, 0.044) 0.23 26 0.082 −0.007 (−0.020, 0.006) 0.29
  ≥0.15 41 0.230 0.021 (0.000, 0.043) 0.054 33 0.079 −0.009 (−0.020, 0.002) 0.11
TBT <0.10 31 0.224 ref   26 0.086 ref  
  0.10–0.4 39 0.217 0.005 (−0.018, 0.029) 0.64 34 0.084 −0.007 (−0.022, 0.008) 0.36
  >0.4 32 0.235 0.024 (0.003, 0.044) 0.024 26 0.078 −0.011 (−0.024, 0.003) 0.12
TPhT <0.02 60 0.227 ref   49 0.080 ref  
  ≥0.02 42 0.220 0.005 (−0.016, 0.027) 0.62 37 0.085 0.002 (−0.008, 0.011) 0.74
Sum of OTCs <0.25 26 0.220 ref   22 0.083 ref  
  0.25–0.50 31 0.228 0.025 (−0.002, 0.052) 0.065 27 0.086 <0.001 (−0.016, 0.016) 1.00
  >0.50 45 0.225 0.018 (−0.001, 0.037) 0.062 37 0.080 −0.008 (−0.021, 0.005) 0.21
Organotin compound Conc. (ng/g fw) Length gain 0–3 monhts   Length gain 3–18 monhts  
   N Length gain (cm/week) β (95% CI) p N Length gain (cm/week) β (95% CI) p
DBT <0.10 32 0.83 ref   28 0.34 ref  
  0.10–0.14 30 0.83 0.054 (−0.038, 0.146) 0.25 26 0.33 −0.014 (−0.039, 0.010) 0.25
  ≥0.15 41 0.83 0.047 (−0.021, 0.114) 0.18 33 0.33 −0.008 (−0.027, 0.011) 0.42
TBT <0.10 32 0.82 ref   27 0.34 ref  
  0.10–0.4 39 0.83 −0.015 (−0.085, 0.055) 0.67 34 0.33 −0.025 (−0.048, −0.001) 0.042
  >0.4 32 0.84 0.024 (−0.038, 0.085) 0.45 26 0.34 −0.014 (−0.036, 0.009) 0.22
TPhT <0.02 60 0.83 ref   49 0.34 ref  
  ≥0.02 43 0.83 −0.005 (−0.061, 0.051) 0.86 38 0.34 −0.006 (−0.025, 0.013) 0.54
Sum of OTCs <0.25 27 0.84 ref   23 0.34 ref  
  0.25–0.50 31 0.82 0.012 (−0.084, 0.108) 0.81 27 0.34 −0.012 (−0.042, 0.018) 0.41
  >0.50 45 0.83 0.018 (−0.039, 0.076) 0.53 37 0.33 −0.012 (−0.035, 0.010) 0.29
  1. aAdjusted for maternal age at birth, maternal pregnancy body mass index, diabetes (yes/no) and smoking (yes/no) during pregnancy, and infant weight for gestational age.