Association of placenta organotin concentrations with growth and ponderal index in 110 newborn boys from Finland during the first 18 months of life: a cohort study

Table 4 Associations between categorical OTC concentrations and PI from linear regression analysis weighted for sampling fractions ^a

Organotin compound	Conc (ng/g fw)	PI at birth				PI at 3 months				PI at 18 monhts
Organotin compound	Conc (ng/g fw)	N	mean PI (kg/m³)	β (95% CI)	p	N	mean PI (kg/m³)	β (95% CI)	p	N	mean PI (kg/m³)	β (95% CI)	p
DBT	<0.10	33	26.8	ref		31	27.5	ref		28	20.1	ref
	0.10–0.14	30	26.0	−1.46 (−2.56, −0.35)	0.010		26.7	−1.35 (−2.77, 0.08)	0.063		20.0	−0.79 (−2.36, 0.79)	0.32
	≥0.15	42	27.4	−0.45 (−1.55, 0.66)	0.43	30 41	28.2	−0.10 (−1.15, 1.13)	0.99	26 33	20.0	−0.93 (−2.04, 0.18)	0.098
TBT	<0.10	33	26.5	ref		31	27.4	ref		27	20.0	ref
	0.10–0.39	40	26.6	−1.36 (−2.90, 0.18)	0.084	39	26.9	−0.28 (−1.79, 1.24)	0.72		20.2	0.46 (−0.97, 1.90)	0.52
	≥0.40	32	27.5	−0.26 (−1.63, 1.12)	0.71	32	28.5	0.85 (−0.20, 1.90)	0.11	34 26	19.9	−0.38 (−1.33, 0.57)	0.43
TPhT	<0.02	61	27.0	ref		60	27.9	ref		49	20.1	ref
	≥0.02	44	26.6	−0.75 (−1.56, 0.06)	0.068	42	27.0	−0.24 (−1.20, 0.73)	0.63	38	20.1	0.21 (−0.67, 1.09)	0.63
Sum of OTCs	<0.25	27	27.1	ref		26	27.3	ref		23	19.8	ref
	0.25–0.49	32	26.0	−1.23 (−2.69, 0.24)	0.10	31	27.2	0.57 (−1.03, 2.16)	0.48		20.3	1.33 (−0.31, 2.97)	0.11
	≥0.50	46	27.3	−0.53 (−1.79, 0.74)	0.41	45	27.9	0.42 (−0.59, 1.43)	0.41	27 37	20.0	−0.33 (−1.27, 0.60)	0.48

^aAdjusted for maternal age at birth, maternal pregnancy body mass index, diabetes (yes/no) and smoking (yes/no) during pregnancy, and infant weight for gestational age.

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